Nikolaus Gravenstein

Nikolaus Gravenstein, MD

Jerome H. Modell, MD, Professor Of Anesthesiology; Professor Of Neurosurgery And Periodontology

Department: MD-ANESTHESIOLOGY-GENERAL
Business Phone: (352) 273-7094
Business Email: ngravenstein@anest.ufl.edu

About Nikolaus Gravenstein

For Dr. Nikolaus Gravenstein, upholding high standards is a family tradition stretching back 45 years. The University of Florida, College of Medicine, recruited Gravenstein’s father, Joachim Gravenstein, to begin the Department of Anesthesiology in 1958. Dr. Nikolaus Gravenstein is the Jerome H. Modell Professor of Anesthesiology in the Division of Multispecialty Anesthesiology, as well as a Professor of Neurosurgery and Professor of Periodontology at the University of Florida. He received his medical degree from the University of Florida, where he also completed his residency and fellowship. His internship in surgery was completed at the University of Minnesota.

Dr. Gravenstein’s work has led to seven patented innovations, including two monitors for carbon dioxide and a noninvasive method for determining hematocrit and blood levels of hemoglobin and oxygen. He has edited and co-edited multiple textbooks, contributed chapters to 28 books, and has written or contributed to more than 80 articles for refereed publications. Dr. Gravenstein has received much honorable recognition, including being named as Outstanding Specialist by the Consumer Referral Guide “The Best Doctors in America: Southeast Region.”

Board Certifications

  • Anesthesiology
    American Board of Anesthesiology

Clinical Profile

Specialties
  • Anesthesiology
Areas of Interest
  • General anesthesia

Publications

2021
An online, interactive, screen-based simulator for learning basic EEG interpretation.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 42(3):1017-1022 [DOI] 10.1007/s10072-020-04610-3. [PMID] 32700228.
2021
Community-Based Production of Quality Face Masks for Personal Protection During the COVID-19 Pandemic.
American journal of medical quality : the official journal of the American College of Medical Quality. 36(1):17-21 [DOI] 10.1177/1062860620956726. [PMID] 32911956.
2021
The RITE of Passage: Learning Styles and Residency In-Service Training Examination (RITE) Scores.
Cureus. 13(1) [DOI] 10.7759/cureus.12442. [PMID] 33552761.
2020
A Flexible Enclosure to Protect Respiratory Therapists During Aerosol-Generating Procedures.
Respiratory care. 65(12):1923-1932 [DOI] 10.4187/respcare.08568. [PMID] 33229369.
2020
A Methyltransferase Inhibitor (Decitabine) Alleviates Intergenerational Effects of Paternal Neonatal Exposure to Anesthesia With Sevoflurane.
Anesthesia and analgesia. 131(4):1291-1299 [DOI] 10.1213/ANE.0000000000005097. [PMID] 32925350.
2020
Barrier enclosure using a Mayo stand and plastic sheet during cardiopulmonary resuscitation in patients and its effect on reducing visible aerosol dispersion on healthcare workers.
Journal of critical care. 59:108-111 [DOI] 10.1016/j.jcrc.2020.05.007. [PMID] 32653587.
2020
Does the Technique for Assessing Loss of Resistance Alter the Magnitude of Epidural Needle Tip Overshoot?
Simulation in healthcare : journal of the Society for Simulation in Healthcare. 15(3):154-159 [DOI] 10.1097/SIH.0000000000000419. [PMID] 32168291.
2020
Isolation gowns as a potential work hazard.
Annals of work exposures and health. 64(6):596-603 [DOI] 10.1093/annweh/wxaa047. [PMID] 32374388.
2020
Neonatal exposure to sevoflurane expands the window of vulnerability to adverse effects of subsequent exposure to sevoflurane and alters hippocampal morphology via decitabine-sensitive mechanisms.
Neuroscience letters. 735 [DOI] 10.1016/j.neulet.2020.135240. [PMID] 32650051.
2020
Roles of Testosterone and Estradiol in Mediation of Acute Neuroendocrine and Electroencephalographic Effects of Sevoflurane During the Sensitive Period in Rats.
Frontiers in endocrinology. 11 [DOI] 10.3389/fendo.2020.545973. [PMID] 33101193.
2019
Intergenerational Effects of Sevoflurane in Young Adult Rats.
Anesthesiology. 131(5):1092-1109 [DOI] 10.1097/ALN.0000000000002920. [PMID] 31517640.
2019
The Effect of Modified Ultrafiltration on Serum Vancomycin Levels During Cardiopulmonary Bypass in Cardiac Surgery.
Journal of cardiothoracic and vascular anesthesia. 33(1):102-106 [DOI] 10.1053/j.jvca.2018.06.004. [PMID] 30143360.
2019
Ventilation Is an Important Confounding Variable When End-Tidal Carbon Dioxide Is Used to Help Guide Cardiopulmonary Resuscitation.
Anesthesia and analgesia. 129(5):1436-1438 [DOI] 10.1213/ANE.0000000000004409. [PMID] 31490249.
2018
Break Scrub to Take That Phone Call?
Journal of the American College of Surgeons. 226(6):1117-1121 [DOI] 10.1016/j.jamcollsurg.2018.03.002. [PMID] 29524662.
2018
Clinical application of limiting laryngeal mask airway cuff pressures utilizing inflating syringe intrinsic recoil.
Romanian journal of anaesthesia and intensive care. 25(1):11-18 [DOI] 10.21454/rjaic.7518.251.cuf. [PMID] 29756057.
2018
Effects of combined brief etomidate anesthesia and postnatal stress on amygdala expression of Cl- cotransporters and corticotropin-releasing hormone and alcohol intake in adult rats.
Neuroscience letters. 685:83-89 [DOI] 10.1016/j.neulet.2018.08.019. [PMID] 30125644.
2018
Error: Blood Pressure and Irmageddon.
Anesthesia and analgesia. 126(4):1112-1115 [DOI] 10.1213/ANE.0000000000002768. [PMID] 29547416.
2018
Misguided by INR in Liver Disease Patients? Implications for Clinicians Including Pain Proceduralists.
Anesthesia and analgesia. 127(1):289-294 [DOI] 10.1213/ANE.0000000000002639. [PMID] 29381517.
2018
Pre-emptive ice cube cryotherapy for reducing pain from local anaesthetic injections for simple lacerations: a randomised controlled trial.
Emergency medicine journal : EMJ. 35(2):103-107 [DOI] 10.1136/emermed-2017-206585. [PMID] 29025864.
2018
Role of epigenetic mechanisms in transmitting the effects of neonatal sevoflurane exposure to the next generation of male, but not female, rats.
British journal of anaesthesia. 121(2):406-416 [DOI] 10.1016/j.bja.2018.04.034. [PMID] 30032879.
2018
Simultaneous Color Change at Opposite Ends of Carbon Dioxide Absorbent Canisters.
Anesthesiology. 129(6) [DOI] 10.1097/ALN.0000000000002415. [PMID] 30161037.
2018
Visualization Improves Supraclavicular Access to the Subclavian Vein in a Mixed Reality Simulator.
Anesthesia and analgesia. 127(1):83-89 [DOI] 10.1213/ANE.0000000000002572. [PMID] 29200069.
2017
Back to the Future: Will Noninvasive Hemoglobin Follow the Glucose Measurement Path?
Anesthesia and analgesia. 124(6):1749-1751 [DOI] 10.1213/ANE.0000000000001816. [PMID] 28525500.
2017
Higher Fresh Gas Flow Rates Decrease Tidal Volume During Pressure Control Ventilation.
Anesthesia and analgesia. 124(5):1506-1511 [DOI] 10.1213/ANE.0000000000001944. [PMID] 28333703.
2017
Incorporating airway examination photography into the electronic record.
Romanian journal of anaesthesia and intensive care. 24(1):7-11 [DOI] 10.21454/rjaic.7518.241.sap. [PMID] 28913492.
2017
Perfusion Index: An Indicator of Success During Endoscopic Thoracic Sympathectomy for Hyperhidrosis.
The Annals of thoracic surgery. 104(2):426-430 [DOI] 10.1016/j.athoracsur.2017.02.023. [PMID] 28527965.
2017
Role of environmental stressors in determining the developmental outcome of neonatal anesthesia.
Psychoneuroendocrinology. 81:96-104 [DOI] 10.1016/j.psyneuen.2017.04.001. [PMID] 28433802.
2017
Simulation-Based Assessment Identifies Longitudinal Changes in Cognitive Skills in an Anesthesiology Residency Training Program.
Journal of patient safety. [DOI] 10.1097/PTS.0000000000000392. [PMID] 28582277.
2016
[Injuries to blood vessels near the heart caused by central venous catheters].
Der Anaesthesist. 65(11):866-871 [PMID] 27709274.
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2016
Acute and Chronic Kidney Disease and Cardiovascular Mortality After Major Surgery.
Annals of surgery. 264(6):987-996 [PMID] 26756753.
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2016
Anesthesiology mentoring.
Current opinion in anaesthesiology. 29(6):698-702 [PMID] 27764048.
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2016
In Response.
Anesthesia and analgesia. 122(2) [DOI] 10.1213/ANE.0000000000000982. [PMID] 26797562.
2016
Intravenous Air: The Partially Invisible Phenomenon.
Anesthesia and analgesia. 123(5):1149-1155 [PMID] 27749346.
View on: PubMed
2016
Long-axis view for ultrasound-guided central venous catheter placement via the internal jugular vein.
Romanian journal of anaesthesia and intensive care. 23(1):27-31 [DOI] 10.21454/rjaic.7518.231.axs. [PMID] 28913474.
2016
No-fault compensation for ventilator-dependent children: a reasonable settlement value for lifetime attendant care.
Risk management and healthcare policy. 9:193-9 [DOI] 10.2147/RMHP.S108238. [PMID] 27574476.
2016
Propofol emulsion-free drug concentration is similar between batches and stable over time.
Romanian journal of anaesthesia and intensive care. 23(1):7-11 [DOI] 10.21454/rjaic.7518.231.emf. [PMID] 28913471.
2016
Propofol, but not etomidate, increases corticosterone levels and induces long-term alteration in hippocampal synaptic activity in neonatal rats.
Neuroscience letters. 618:1-5 [DOI] 10.1016/j.neulet.2016.02.045. [PMID] 26923669.
2016
Race-Specific Pharmacodynamic Model of Propofol-Induced Loss of Consciousness.
Journal of clinical pharmacology. 56(9):1141-50 [DOI] 10.1002/jcph.716. [PMID] 26865382.
2016
Role of Steroids in Hyperexcitatory Adverse and Anesthetic Effects of Sevoflurane in Neonatal Rats.
Neuroendocrinology. 103(5):440-51 [DOI] 10.1159/000437267. [PMID] 26159049.
2016
Still Waiting for Evidence That Current Noninvasive Hemoglobinometry Adds Value.
Anesthesia and analgesia. 123(3):796-7 [DOI] 10.1213/ANE.0000000000001405. [PMID] 27258070.
2016
Use-Dependent Curvature Changes in the GlideRite® Reusable Intubation Stylet.
A & A case reports. 6(10):299-304 [DOI] 10.1213/XAA.0000000000000303. [PMID] 27075422.
2015
Anesthesia with sevoflurane in neonatal rats: Developmental neuroendocrine abnormalities and alleviating effects of the corticosteroid and Cl(-) importer antagonists.
Psychoneuroendocrinology. 60:173-81 [DOI] 10.1016/j.psyneuen.2015.06.016. [PMID] 26150359.
2015
Evaluation of the Head-Mounted Display for Ultrasound-Guided Peripheral Nerve Blocks in Simulated Regional Anesthesia.
Pain medicine (Malden, Mass.). 16(11):2192-4 [DOI] 10.1111/pme.12765. [PMID] 25930716.
2015
Joint Commission and Regulatory Fatigue/Weakness/Overabundance/Distraction: Clinical Context Matters.
Anesthesia and analgesia. 121(2):394-6 [DOI] 10.1213/ANE.0000000000000732. [PMID] 26197372.
2015
Leaving more than your fingerprint on the intravenous line: a prospective study on propofol anesthesia and implications of stopcock contamination.
Anesthesia and analgesia. 120(4):861-7 [DOI] 10.1213/ANE.0b013e318292ed45. [PMID] 23749446.
2015
Prevalence of dependent loops in urinary drainage systems in hospitalized patients.
Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society. 42(3):273-8 [DOI] 10.1097/WON.0000000000000137. [PMID] 25945825.
2015
Prophylactic perioperative antibiotic administration: is it time to infuse our practices with new approaches?
Anesthesia and analgesia. 120(4):709-11 [DOI] 10.1213/ANE.0000000000000541. [PMID] 25790201.
2015
Propofol-induced electroencephalographic seizures in neonatal rats: the role of corticosteroids and γ-aminobutyric acid type A receptor-mediated excitation.
Anesthesia and analgesia. 120(2):433-9 [DOI] 10.1213/ANE.0000000000000529. [PMID] 25390279.
2015
What is a reference standard?
Anesthesia and analgesia. 120(1):8-9 [DOI] 10.1213/ANE.0000000000000426. [PMID] 25625249.
2014
A mixed-reality part-task trainer for subclavian venous access.
Simulation in healthcare : journal of the Society for Simulation in Healthcare. 9(1):56-64 [DOI] 10.1097/SIH.0b013e31829b3fb3. [PMID] 24310163.
2014
A quantitative analysis of the relation between the clavicular tilt angle and subclavian central venous catheter misplacement.
Clinical and experimental emergency medicine. 1(2):114-119 [PMID] 27752562.
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2014
Are anesthesia start and end times randomly distributed? The influence of electronic records.
Journal of clinical anesthesia. 26(4):264-70 [DOI] 10.1016/j.jclinane.2013.10.016. [PMID] 24856798.
2014
Construct Validity and Generalizability of Simulation-Based Objective Structured Clinical Examination Scenarios.
Journal of graduate medical education. 6(3):489-94 [DOI] 10.4300/JGME-D-13-00356.1. [PMID] 26279774.
2014
Endocrine and neurobehavioral abnormalities induced by propofol administered to neonatal rats.
Anesthesiology. 121(5):1010-7 [DOI] 10.1097/ALN.0000000000000366. [PMID] 24992523.
2014
Foley drainage tubing configuration affects bladder pressure: a bench model study.
Urologic nursing. 34(1):33-7 [PMID] 24716379.
View on: PubMed
2014
Response to Al-Khabori M. et al.’s “validation of a non-invasive pulse CO-oximetry based hemoglobin estimation in normal blood donors,” Transfusion and Apheresis Science 2013 Nov 4. Accurate enough for blood donors? Not so fast.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 51(1) [DOI] 10.1016/j.transci.2014.02.027. [PMID] 25129830.
2014
Retrospective computed tomography mapping of intrapleural air may demonstrate optimal window for ultrasound diagnosis of pneumothorax.
Journal of intensive care medicine. 29(6):342-7 [DOI] 10.1177/0885066613488735. [PMID] 23753251.
2014
Screening for anemia: is this ready for prime time?
Pediatrics international : official journal of the Japan Pediatric Society. 56(3) [DOI] 10.1111/ped.12358. [PMID] 24894936.
2014
Simulation-based assessment to evaluate cognitive performance in an anesthesiology residency program.
Journal of graduate medical education. 6(1):85-92 [DOI] 10.4300/JGME-D-13-00230.1. [PMID] 24701316.
2014
Virtual humans for inter-ethnic variability training in sedation and analgesia.
Studies in health technology and informatics. 196:175-81 [PMID] 24732502.
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2013
Automated, real-time fresh gas flow recommendations alter isoflurane consumption during the maintenance phase of anesthesia in a simulator-based study.
Anesthesia and analgesia. 117(5):1139-47 [DOI] 10.1213/ANE.0b013e3182a08d90. [PMID] 24108253.
2013
Developmental effects of neonatal isoflurane and sevoflurane exposure in rats.
Anesthesiology. 119(2):358-64 [DOI] 10.1097/ALN.0b013e318291c04e. [PMID] 23619170.
2013
Developmental Effects of Sevoflurane in Rats May Involve the Anesthetic-Caused Dysregulation of the Hypothalamic-Pituitary-Adrenal (Hpa) Axis
Anesthesia and Analgesia. 116(1)
2013
Differentiating inspiratory and expiratory valve malfunctions.
Anesthesiology. 119(2) [DOI] 10.1097/ALN.0b013e318299f3fd. [PMID] 23880994.
2013
Head position angles to open the upper airway differ less with the head positioned on a support.
The American journal of emergency medicine. 31(1):80-5 [DOI] 10.1016/j.ajem.2012.06.007. [PMID] 22944550.
2013
Noninvasive hemoglobin monitoring: how accurate is enough?
Anesthesia and analgesia. 117(4):902-7 [DOI] 10.1213/ANE.0b013e31829483fb. [PMID] 23842195.
2013
Patient repositioning and pressure ulcer risk–monitoring interface pressures of at-risk patients.
Journal of rehabilitation research and development. 50(4):477-88 [PMID] 23934869.
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2013
Prevention of airway fires: do not overlook the expired oxygen concentration.
Anesthesia and analgesia. 117(5):1172-6 [DOI] 10.1213/ANE.0b013e318298a692. [PMID] 23835452.
2013
Reduction of conditioned pain modulation in humans by naltrexone: an exploratory study of the effects of pain catastrophizing.
Journal of behavioral medicine. 36(3):315-27 [DOI] 10.1007/s10865-012-9424-2. [PMID] 22534819.
2013
Selection of an aptamer antidote to the anticoagulant drug bivalirudin.
PloS one. 8(3) [DOI] 10.1371/journal.pone.0057341. [PMID] 23483901.
2012
Intravenous fluids cause systemic bias in a conductivity-based point-of-care hematocrit meter.
Anesthesia and analgesia. 114(2):314-21 [DOI] 10.1213/ANE.0b013e31823fecbd. [PMID] 22156329.
2012
Roles of aldosterone and oxytocin in abnormalities caused by sevoflurane anesthesia in neonatal rats.
Anesthesiology. 117(4):791-800 [PMID] 22854980.
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2011
A bit confused.
Anesthesia and analgesia. 112(6):1509; author reply 1509-10 [DOI] 10.1213/ANE.0b013e31821d121c. [PMID] 21613202.
2011
Artifactual increase in journal self-citation.
Anesthesia and analgesia. 113(2):378-82 [DOI] 10.1213/ANE.0b013e31821d72e5. [PMID] 21596873.
2011
Assessing point-of-care hemoglobin measurement: be careful we don’t bias with bias.
Anesthesia and analgesia. 113(6):1289-91 [DOI] 10.1213/ANE.0b013e31822906b2. [PMID] 22116964.
2011
Continuous transthoracic echocardiography in a 93-year-old patient with hypertrophic cardiomyopathy during electroconvulsive therapy.
The journal of ECT. 27(3):224-6 [DOI] 10.1097/YCT.0b013e318223821b. [PMID] 21865958.
2011
Let’s end the error of the standard error.
Anesthesia and analgesia. 112(1) [DOI] 10.1213/ANE.0b013e3181f2c0cd. [PMID] 21173215.
2011
Let’s think clinically instead of mathematically about device accuracy.
Anesthesia and analgesia. 113(1):89-91 [DOI] 10.1213/ANE.0b013e318219a290. [PMID] 21519048.
2011
Using the inflating syringe as a safety valve to limit laryngeal mask airway cuff pressure.
Journal of clinical monitoring and computing. 25(6):405-10 [DOI] 10.1007/s10877-011-9319-8. [PMID] 22076616.
2010
All valve malfunctions are not the same.
Anesthesiology. 113(3):758; author reply 758-9 [DOI] 10.1097/ALN.0b013e3181eab908. [PMID] 20733401.
2010
Bumetanide alleviates epileptogenic and neurotoxic effects of sevoflurane in neonatal rat brain.
Anesthesiology. 112(3):567-75 [DOI] 10.1097/ALN.0b013e3181cf9138. [PMID] 20124973.
2010
Effects of turning on skin-bed interface pressures in healthy adults.
Journal of advanced nursing. 66(7):1556-64 [DOI] 10.1111/j.1365-2648.2010.05292.x. [PMID] 20497272.
2010
Mandatory pre-suit mediation: local malpractice reform benefiting patients and healthcare providers.
Journal of healthcare risk management : the journal of the American Society for Healthcare Risk Management. 30(2):27-35 [DOI] 10.1002/jhrm.20050. [PMID] 20979162.
2010
Monitoring technologies in the neonatal intensive care unit: implications for the detection of necrotizing enterocolitis.
Journal of perinatology : official journal of the California Perinatal Association. 30(11):701-8 [DOI] 10.1038/jp.2010.9. [PMID] 20336080.
2010
The anatomical correction of cricoid pressure.
Minerva anestesiologica. 76(4) [PMID] 20332747.
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2010
The anatomy of the cricoid pressure unit.
Surgical and radiologic anatomy : SRA. 32(4) [DOI] 10.1007/s00276-009-0608-6. [PMID] 20033167.
2010
Thromboelastographic and pharmacokinetic profiles of micro- and macro-emulsions of propofol in swine.
Biopharmaceutics & drug disposition. 31(5-6):269-77 [DOI] 10.1002/bdd.709. [PMID] 20578214.
2010
Transfusion has no effect on recurrence in hepatitis C after liver transplantation.
Acta anaesthesiologica Scandinavica. 54(10):1224-32 [PMID] 21069900.
View on: PubMed
2010
What is the preferred central venous pressure zero reference for hepatic resection?
Anesthesia and analgesia. 111(3):660-4 [DOI] 10.1213/ANE.0b013e3181c76d3e. [PMID] 19955507.
2010
Who says bedside glucose measurement is simple (or always accurate)?
Critical care medicine. 38(3) [DOI] 10.1097/CCM.0b013e3181cc4609. [PMID] 20168175.
2009
A cost-effective screening method for preoperative hyperglycemia.
Anesthesia and analgesia. 109(5):1622-4 [DOI] 10.1213/ANE.0b013e3181b7c626. [PMID] 19843800.
2009
All glucose measurements are not equal.
Anesthesiology. 111(5):1160; author reply 1160-1 [DOI] 10.1097/ALN.0b013e3181ba3a35. [PMID] 19858882.
2009
Cricoid pressure results in compression of the postcricoid hypopharynx: the esophageal position is irrelevant.
Anesthesia and analgesia. 109(5):1546-52 [DOI] 10.1213/ane.0b013e3181b05404. [PMID] 19843793.
2009
Intraoperative Red Cell and Platelet Transfusion Have No Effect On Survival Or Histologic Disease Recurrence in Hepatitis C Patients After Liver Transplantation
Liver Transplantation. 15
2009
The Cvp Zero Reference and Hepatic Surgery.
Liver Transplantation. 15:S172-S173
2009
The Need for An Accurate Noninvasive Thermometer Response
Anesthesia and Analgesia. 109(1):288-289 [DOI] 10.1213/ane.0b013e3181a90858.
2009
Warning: increased risk of surgical fire.
Anesthesia and analgesia. 108(5) [DOI] 10.1213/ane.0b013e31819cb62b. [PMID] 19372360.
2008
Body temperature change during anesthesia for electroconvulsive therapy: implications for quality incentives in anesthesiology.
Anesthesia and analgesia. 107(5):1618-20 [DOI] 10.1213/ane.0b013e31817b7c35. [PMID] 18931220.
2008
Effects of elevating the head of bed on interface pressure in volunteers.
Critical care medicine. 36(11):3038-42 [DOI] 10.1097/CCM.0b013e31818b8dbd. [PMID] 18824905.
2008
Interactive web simulation for propofol and fospropofol, a new propofol prodrug.
Anesthesia and analgesia. 106(3):880-3, table of contents [DOI] 10.1213/ane.0b013e3181614fae. [PMID] 18292434.
2008
Lung isolation using a laryngeal mask airway and a bronchial blocker in a patient with a recent tracheostomy.
Journal of cardiothoracic and vascular anesthesia. 22(6):883-6 [DOI] 10.1053/j.jvca.2007.09.007. [PMID] 18834756.
2008
Partial right atrial inflow occlusion for controlled systemic hypotension during thoracic endovascular aortic repair.
Journal of vascular surgery. 48(2):494-8 [DOI] 10.1016/j.jvs.2008.03.003. [PMID] 18644496.
2008
Role of simulators, educational programs, and nontechnical skills in anesthesia resident selection, education, and competency assessment.
Journal of critical care. 23(2):167-72 [DOI] 10.1016/j.jcrc.2007.11.009. [PMID] 18538207.
2007
Central venous catheter insertion: it is finally time to start looking.
Anesthesia and analgesia. 105(3) [PMID] 17717258.
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2007
Temperature-related differences in mean expired pump and arterial carbon dioxide in patients undergoing cardiopulmonary bypass.
Journal of cardiothoracic and vascular anesthesia. 21(1):57-60 [PMID] 17289481.
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2006
An accuracy evaluation of the T-Line Tensymeter (continuous noninvasive blood pressure management device) versus conventional invasive radial artery monitoring in surgical patients.
Anesthesia and analgesia. 102(2):484-90 [PMID] 16428547.
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2006
An audible indication of exhalation increases delivered tidal volume during bag valve mask ventilation of a patient simulator.
Anesthesia and analgesia. 102(1):168-71 [PMID] 16368824.
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2006
Dilutional hypokalemia-induced arrhythmias associated with intraoperative cell salvage and reinfusion.
Journal of cardiothoracic and vascular anesthesia. 20(4):568-9 [PMID] 16884991.
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2006
Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.
Recent patents on CNS drug discovery. 1(3):261-70 [PMID] 18221208.
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2006
Persistent ST elevation and new regional wall motion abnormalities without evidence of coronary artery obstruction following surgical repair of an endocarditic aortic valve.
Journal of cardiothoracic and vascular anesthesia. 20(3):397-400 [PMID] 16750745.
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2006
Preparation and anesthetic properties of propofol microemulsions in rats.
Anesthesiology. 104(6):1184-90 [PMID] 16732089.
View on: PubMed
2005
Differential modulation of glutamatergic transmission by 3,5-dibromo-L-phenylalanine.
Molecular pharmacology. 67(5):1648-54 [PMID] 15687225.
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2005
Oximetry-derived perfusion index for intraoperative identification of successful thoracic sympathectomy.
The Annals of thoracic surgery. 80(2):467-70 [PMID] 16039187.
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2005
Reducing the incidence of surgical fires: supplying nasal cannulae with sub-100% O2 gas mixtures from anesthesia machines.
Anesthesia and analgesia. 101(5):1407-12 [PMID] 16244002.
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2005
The effect of a bellows leak in an Ohmeda 7810 ventilator on room contamination, inspired oxygen, airway pressure, and tidal volume.
Anesthesia and analgesia. 101(1):151-4, table of contents [PMID] 15976223.
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2004
Intraoperative transesophageal echocardiography detects a sheared catheter wire and alters surgical approach in a Jehovah’s Witness patient undergoing coronary artery bypass graft surgery.
Journal of cardiothoracic and vascular anesthesia. 18(6):765-6 [PMID] 15650989.
View on: PubMed
2004
Measurement of cardiac output before and after cardiopulmonary bypass: Comparison among aortic transit-time ultrasound, thermodilution, and noninvasive partial CO2 rebreathing.
Journal of cardiothoracic and vascular anesthesia. 18(5):563-72 [PMID] 15578466.
View on: PubMed
2004
The effect of body inclination during prone positioning on intraocular pressure in awake volunteers: a comparison of two operating tables.
Anesthesia and analgesia. 99(4):1152-8, table of contents [PMID] 15385367.
View on: PubMed
2003
Central venous catheter tip and perforation.
Anesthesia and analgesia. 96(1):301-2; author reply 302 [PMID] 12505972.
View on: PubMed
2003
Strategies to prevent arterial injury caused by dilator should be integrated into routine clinical practice.
Anesthesia and analgesia. 96(6) [PMID] 12761026.
View on: PubMed
2002
A better landmark for positioning a central venous catheter.
Journal of clinical monitoring and computing. 17(6):331-4 [PMID] 12885176.
View on: PubMed
2002
Detection of oxygen delivery failure during cardiopulmonary bypass: an even earlier warning technique.
Journal of cardiothoracic and vascular anesthesia. 16(6) [PMID] 12486667.
View on: PubMed
2002
Unilateral cerebral oxygen desaturation during emergent repair of a DeBakey type 1 aortic dissection: potential aversion of a major catastrophe.
Anesthesiology. 96(5):1263-5 [PMID] 11981170.
View on: PubMed
2002
Venous air embolism during changes in patient position or ventilation: an etiology for postoperative cardiovascular collapse?
Anesthesia and analgesia. 95(5):1465-6; author reply 1466 [PMID] 12401655.
View on: PubMed
2000
Effects of milrinone versus epinephrine on grafted internal mammary artery flow after cardiopulmonary bypass.
Journal of cardiothoracic and vascular anesthesia. 14(1):9-11 [PMID] 10698384.
View on: PubMed
2000
Milrinone, not epinephrine, improves left ventricular compliance after cardiopulmonary bypass.
Journal of cardiothoracic and vascular anesthesia. 14(4):374-7 [PMID] 10972599.
View on: PubMed
1999
Central venous pressure monitoring during bypass.
Anesthesia and analgesia. 89(5):1326-7 [PMID] 10553864.
View on: PubMed
1999
Growth of Staphylococcus aureus in Diprivan and Intralipid: implications on the pathogenesis of infections.
Anesthesiology. 91(5):1394-400 [PMID] 10551591.
View on: PubMed
1999
Spinal anesthesia for nonpulmonary surgery in a lung transplant recipient.
Journal of neurosurgical anesthesiology. 11(1):46-8 [PMID] 9890386.
View on: PubMed
1997
Dilator-associated complications of central vein catheter insertion: possible mechanisms of injury and suggestions for prevention.
Journal of cardiothoracic and vascular anesthesia. 11(4):539-40; author reply 541 [PMID] 9188013.
View on: PubMed
1997
Intraoperative usefulness of transesophageal echocardiography: detection of unsuspected rupture of an aneurysm of the sinus of Valsalva.
Journal of cardiothoracic and vascular anesthesia. 11(5):619-21 [PMID] 9263098.
View on: PubMed
1997
Monitoring of ventilation on and off cardiopulmonary bypass: two standards or one?
Anesthesia and analgesia. 84(3):703-4 [PMID] 9052336.
View on: PubMed
1997
Multilumen central venous catheters in children: relative potential to perforate vessels. An in vitro study.
Journal of clinical monitoring. 13(2):75-9 [PMID] 9112202.
View on: PubMed
1997
Very limited air elimination capability of the level 1 fluid warmer.
Journal of clinical anesthesia. 9(3):233-5 [PMID] 9172032.
View on: PubMed
1996
Epidural catheter reconnection. Safe and unsafe practice.
Anesthesiology. 85(4):883-8 [PMID] 8873560.
View on: PubMed
1996
Head rotation during internal jugular vein cannulation and the risk of carotid artery puncture.
Anesthesia and analgesia. 82(1):125-8 [PMID] 8712386.
View on: PubMed
1996
Magnetron-based inline microwave fluid warmer.
Journal of clinical monitoring. 12(3):271-6 [PMID] 8823652.
View on: PubMed
1995
Against routine postoperative oxygen administration in the PACU.
Journal of clinical monitoring. 11(6):408-10 [PMID] 8576726.
View on: PubMed
1994
Computer-modulated patient-controlled analgesia. Preliminary evaluation of a prototype.
Regional anesthesia. 19(4):270-6 [PMID] 7947428.
View on: PubMed
1994
Intraoperative pulse oximetry: frequency and distribution of discrepant data.
Journal of clinical anesthesia. 6(6):491-5 [PMID] 7880513.
View on: PubMed
1994
Lack of uniform definitions and reporting in laboratory models of cardiac arrest: a review of the literature and a proposal for guidelines.
Annals of emergency medicine. 23(1):9-16 [PMID] 8273965.
View on: PubMed
1994
Postoperative information transfer: a study comparing two university hospitals.
International journal of clinical monitoring and computing. 11(3):145-9 [PMID] 7829932.
View on: PubMed
1994
Pulse oximetry monitoring can change routine oxygen supplementation practices in the postanesthesia care unit.
Anesthesia and analgesia. 78(2):365-8 [PMID] 8311292.
View on: PubMed
1992
Low back pain following epidural blood patch.
Journal of clinical anesthesia. 4(5):413-8 [PMID] 1389199.
View on: PubMed
1992
More on accidental arterial cannulation after attempted central venipuncture.
Critical care medicine. 20(4) [PMID] 1559377.
View on: PubMed
1992
More on risk factors for central venous catheter-related vascular erosions.
JPEN. Journal of parenteral and enteral nutrition. 16(6):595-6 [PMID] 1494225.
View on: PubMed
1992
Pericardial tamponade secondary to perforation by central venous catheters in orthopaedic patients.
The Journal of bone and joint surgery. American volume. 74(7):1110-1 [PMID] 1522101.
View on: PubMed
1991
An approach to spinal or epidural catheters that are difficult to remove.
Anesthesiology. 75(3) [PMID] 1741861.
View on: PubMed
1991
Duration of carbon dioxide absorption by soda lime at low rates of fresh gas flow.
Journal of clinical anesthesia. 3(2):104-7 [PMID] 1903949.
View on: PubMed
1991
In vitro comparison of central venous catheters for aspiration of venous air embolism: effect of catheter type, catheter tip position, and cardiac inclination.
Journal of clinical anesthesia. 3(4):290-4 [PMID] 1910796.
View on: PubMed
1991
In vitro evaluation of relative perforating potential of central venous catheters: comparison of materials, selected models, number of lumens, and angles of incidence to simulated membrane.
Journal of clinical monitoring. 7(1):1-6 [PMID] 1999693.
View on: PubMed
1991
Increased pulmonary artery perforating potential of pulmonary artery catheters during hypothermia.
Journal of cardiothoracic and vascular anesthesia. 5(3):234-6 [PMID] 1863743.
View on: PubMed
1990
Infrared analysis of volatile anesthetics: impact of monitor agent setting, volatile mixtures, and alcohol.
Journal of clinical monitoring. 6(3):203-6 [PMID] 2380750.
View on: PubMed
1990
Passive warming of airway gases (artificial nose) improves accuracy of esophageal temperature monitoring.
Journal of clinical monitoring. 6(2):89-92 [PMID] 2352008.
View on: PubMed
1990
Postoperative sore throat: effect of oropharyngeal airway in orotracheally intubated patients.
Anesthesia and analgesia. 70(5):512-6 [PMID] 2331067.
View on: PubMed
1989
Capnometry in infants should not be done at lower sampling flow rates.
Journal of clinical monitoring. 5(1):63-4 [PMID] 2494305.
View on: PubMed
1989
Endobronchial rupture from endotracheal reintubation with an endotracheal tube guide.
Journal of clinical anesthesia. 1(3):214-7 [PMID] 2627389.
View on: PubMed
1989
High incidence of CO2 laser beam contact with the tracheal tube during operations on the upper airway.
Journal of clinical anesthesia. 1(5):354-7 [PMID] 2516733.
View on: PubMed
1989
Incidence of oxygen desaturation during oral surgery outpatient procedures.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 47(2):147-9 [PMID] 2913248.
View on: PubMed
1989
More on thermoregulatory thresholds with halothane.
Anesthesiology. 70(2):370-1 [PMID] 2913879.
View on: PubMed
1988
Evaluation of helium interference with mass spectrometry.
Anesthesia and analgesia. 67(9):887-9 [PMID] 3137838.
View on: PubMed
1988
Extracorporeal shock-wave lithotripsy (ESWL). II. In vivo canine results of blast path treatment of human gallstones.
The Journal of surgical research. 44(5):578-88 [PMID] 3374122.
View on: PubMed
1988
More on eliminating CT scan artifact due to endotracheal tubes.
Anesthesiology. 68(5) [PMID] 3369738.
View on: PubMed
1988
Simulation of ventilatory-induced stone movement and its effect on stone fracture during extracorporeal shock wave lithotripsy.
The Journal of urology. 140(2):405-7 [PMID] 3398162.
View on: PubMed
1988
Use of breathing-circuit stethoscopes can have complications.
Anesthesia and analgesia. 67(4) [PMID] 3354884.
View on: PubMed
1987
Capnogram artifact during high airway pressures caused by a water trap.
Anesthesia and analgesia. 66(2):185-7 [PMID] 3101548.
View on: PubMed
1987
Capnography and the Bain circuit II: Validation of a computer model.
Journal of clinical monitoring. 3(3):165-77 [PMID] 3112317.
View on: PubMed
1987
Computer-assisted capnogram analysis.
Journal of clinical monitoring. 3(3):194-200 [PMID] 3112319.
View on: PubMed
1987
Continuous neonatal evaluation in the delivery room by pulse oximetry.
Journal of clinical monitoring. 3(2):96-100 [PMID] 3585439.
View on: PubMed
1987
Effects of aortic occlusion on regional spinal cord blood flow and somatosensory evoked potentials in sheep.
Neurosurgery. 21(5):668-75 [PMID] 3696400.
View on: PubMed
1987
Methylene blue and indocyanine green artifactually lower pulse oximetry readings of oxygen saturation. Studies in dogs.
Journal of clinical monitoring. 3(4):249-56 [PMID] 3681358.
View on: PubMed
1987
Preventing ambient light from affecting pulse oximetry.
Anesthesiology. 67(2) [PMID] 3605758.
View on: PubMed
1987
Pulse oximetry fails to accurately detect low levels of arterial hemoglobin oxygen saturation in dogs.
Journal of clinical monitoring. 3(4):257-62 [PMID] 3681359.
View on: PubMed
1987
Thoracic aortic occlusion: somatosensory evoked potential monitoring and neurologic outcome in a canine model.
Surgical neurology. 28(5):351-60 [PMID] 3660205.
View on: PubMed
1987
Tidal volume changes due to the interaction of anesthesia machine and anesthesia ventilator.
Journal of clinical monitoring. 3(3):187-90 [PMID] 3475406.
View on: PubMed
1986
A lung model of carbon dioxide concentrations with mechanical or spontaneous ventilation.
Critical care medicine. 14(12):1055-7 [PMID] 3096636.
View on: PubMed
1986
Effects of induced hypotension during experimental vasospasm: a neurological, electrophysiological, and pathological analysis.
Neurosurgery. 19(1):41-8 [PMID] 3748337.
View on: PubMed
1985
Clinical relevance of long-latency SEPs and VEPs during coma and emergence from coma.
Electroencephalography and clinical neurophysiology. 62(2):88-98 [PMID] 2578947.
View on: PubMed
1985
Factors influencing capnography in the Bain circuit.
Journal of clinical monitoring. 1(1):6-10 [PMID] 4093790.
View on: PubMed
1985
Misleading mass spectrometer reading caused by an aerosol propellant.
Anesthesiology. 62(1):70-2 [PMID] 3966673.
View on: PubMed
1985
More on mass spectrometers and aerosol propellants.
Anesthesiology. 63(5):568-9 [PMID] 4051228.
View on: PubMed
1985
Pulse oximetry for early detection of hypoxemia in anesthetized infants.
Journal of clinical monitoring. 1(2):135-7 [PMID] 3831254.
View on: PubMed
1985
The oxygenator arterial sampling port: a potential source of error.
Anesthesiology. 62(6):825-6 [PMID] 4003813.
View on: PubMed
1984
Mass spectrometry and the inspiratory-to-expiratory ratio.
Anesthesia and analgesia. 63(12) [PMID] 6239573.
View on: PubMed
1984
Pitfalls with mass spectrometry in clinical anesthesia.
International journal of clinical monitoring and computing. 1(1):27-34 [PMID] 6571214.
View on: PubMed
1977
Comparison of central corneal endothelial cell numbers with peripheral areas.
American journal of ophthalmology. 84(4):473-6 [PMID] 910851.
View on: PubMed
1976
Scanning electron microscopy of postoperative M-K and moist chamber-stored corneas.
Investigative ophthalmology. 15(4):260-6 [PMID] 770384.
View on: PubMed
1976
The effect of 10-0 running nylon versus 8-0 silk on the healing of corneal gragts.
Annals of ophthalmology. 8(1):99-102 [PMID] 1108736.
View on: PubMed
1975
[The effect of Actihaemyl on epithelial regeneration (author’s transl)].
Klinische Monatsblatter fur Augenheilkunde. 167(3):437-41 [PMID] 1214422.
View on: PubMed
1975
Aspirin stabilization of the blood-aqueous barrier in the human eye.
American journal of ophthalmology. 79(5):817-9 [PMID] 807111.
View on: PubMed

Grants

Mar 2021 ACTIVE
Virtual Operating Room Simulation Clinical Immersion Program
Role: Principal Investigator
Funding: Merck Sharp & Dohme
Jun 2020 ACTIVE
Refining genetic characteristics of Malignant Hyperthermia (MH)
Role: Principal Investigator
Funding: NATL INST OF HLTH NHGRI
Oct 2017 ACTIVE
Malignant Hyperthermia Association of the United States (MHAUS)
Role: Principal Investigator
Funding: MALIGNANT HYPERTHERMIA ASSO OF THE U S

Patents

Issued May 2018
Context-Sensitive Flow Interrupter and Drainage Outflow Optimization System
#9,962,516
Issued January 2018
Patient In-The-Loop Participatory Care and Monitoring
#9,881,133
Published January 2018
Patient In-The-Loop Participatory Care and Monitoring (CON)
#US-2018-0226142-A1
Published December 2017
Guided Orthodontic Bracket Application
#US-2018-0140381 A1
Published November 2017
Urologic Sheath with Photodiode and Coaxial Grabber for Suctioning of Larger Kidney Stones
#WO 2018/098477
Published September 2017
Context-Sensitive Clamp for Urine Back Flow Prevention (CON)
#US-2018-0015251-A1
Issued April 2017
Interactive Mixed Reality Trainer (CON)
#9,626,805
Issued February 2016
Interactive Mixed Reality System and Uses Thereof
#9,251,721
Issued December 2015
Acoustic System for Monitoring the Performance of Left Ventricle Assist Devices and Other Mechanical DevicesImplanted in a Patient's Body
#9,220,475
Published November 2014
Method and Apparatus for Detecting and/or Analyzing Motion Using Radar and Multiple Identifiable Reflectors
#US-2015-0164379-A1
Issued August 2014
Noninvasive Hemoglobin Measurement
#8,818,472
Issued December 2013
Panoramic Display-Based Interactive Simulation
#8,605,133
Issued October 2013
Materials and Methods for Maintaining Proper Body Temperature
#8,544,115
Issued September 2013
Handwashing Compliance Detection System (CIP)
#8,525,666
Issued July 2011
A Novel Handwashing Compliance Detection System
#7,978,083
Issued July 2010
Handwashing Compliance Detection System
#7,755,494
Published November 2008
Inferior Vena Cava Variable Occlusional Catheter
#UF-2009-0131785-A1
Published January 2007
Methods and Materials for Treating Mental Illness
#US-2008-0096870-A1
Published October 2006
Novel Catheter Sensor
#US-2007-0225584-A1
Published July 2005
Apparatus and Methods to Titrate 02% Delivered to Open Delivery Systems
#US-2006-0150970-A1
Issued October 2003
Novel Microemulsion and MIcelle Syustems for Solubilzing Drugs
#6,638,537
Published October 2003
Novel Microemulsion and Micelle Systems for Solubilizing Drugs
#US-2004-0198813-A
Issued September 2003
Novel Microemulsion and Micelle Systems for Solubilizing Drugs
#6,623,765
Issued December 2000
Transtracheal Energy Application and Sensing System For Intubation: Method and Apparatus
#6,161,537
Issued October 1996
Transtracheal Energy Application and Sensing System for Intubation: Method and Apparatus
#5,560,351
Issued January 1993
System and Method for In-line Heating of Medical Fluid
#5,180,896
Issued May 1990
CO2 Diagnostic Monitor
#4,928,687

Education

Fellowship – Anesthesiology
1984 · University of Florida
Residency – Anesthesiology
1983 · University of Florida
Internship – Surgery
1981 · University of Minnesota
Medical Degree
1980 · University of Florida

Teaching Profile

Courses Taught
2018
MDT7700 Elect Top/Anesthesiol
2018
MDC7700 Req Anes Crit Care
2018
BMS6812 Intro Clin Med 2
2012
DEN8651L Clinical Periodontics
2021
PAS5020 Intro to Medicine 2

Contact Details

Phones:
Business:
(352) 273-7094
Emails: