Patrick J Tighe

Patrick J Tighe, MD, MS

Associate Professor Of Anesthesiology; Donn M. Dennis MD Professorship In Anesthetic Innovation; Co-Director, Perioperative Cognitive Anesthesia Network; Associate Professor Of Orthopaedics And Information Systems And Operations Management

Department: MD-ANESTHESIOLOGY-GENERAL
Business Phone: (352) 273-7844
Business Email: ptighe@ufl.edu

About Patrick J Tighe

Dr. Tighe serves in the Division of Acute Pain Medicine and provides care in the blockroom, acute pain service, and operating room. Additionally, he is the director of the Perioperative Analytic Group and Co-Director of the Perioperative Cognitive Anesthesia Network (PeCAN).

Dr. Tighe’s research examines how machine and deep learning algorithms, decision and process modeling, and social network analyses can improve processes related to acute postoperative pain, cognition, and perioperative patient safety. His work is currently supported by an R01 from the National Institute of General Medical Sciences at the National Institutes of Health to examine the temporal dynamics of postoperative pain. Additionally, he is a Co-PI for PRECEDE, examining the role of perioperative factors associated with postoperative cognition. He collaborates with a diverse array of researchers from the Colleges of Medicine, Engineering, Business, Dentistry, and Pharmacy.

Dr. Tighe serves as section co-editor for the Acute and Perioperative Section of the journal Pain Medicine, and is on the Board of Directors for the American Academy of Pain Medicine. He serves on the committee on Electronic and Media Information Technology (EMIT) at the American Society of Anesthesiologists. In addition, Dr. Tighe has worked with the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) group to develop a new multidimensional taxonomy for acute pain. He recently served as a consultant to the Institute for Healthcare Improvement on behalf of the Anesthesia Patient Safety Foundation for the IHI “Advancing the Safety of Acute Pain Management” initiative.

Board Certifications

  • Anesthesiology
    American Board of Anesthesiology

Clinical Profile

Specialties
  • Anesthesiology

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-1881-9941

Publications

2021
A qualitative analysis of clinicians’ communication strategies with family members of patients experiencing hospital-acquired delirium.
Geriatric nursing (New York, N.Y.). 42(3):694-699 [DOI] 10.1016/j.gerinurse.2021.02.009. [PMID] 33831716.
2021
Association Between Dual Trajectories of Opioid and Gabapentinoid Use and Healthcare Expenditures Among US Medicare Beneficiaries.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 24(2):196-205 [DOI] 10.1016/j.jval.2020.12.001. [PMID] 33518026.
2021
Dual-trajectories of opioid and gabapentinoid use and risk of subsequent drug overdose among Medicare beneficiaries in the United States: a retrospective cohort study.
Addiction (Abingdon, England). 116(4):819-830 [DOI] 10.1111/add.15189. [PMID] 32648951.
2021
On kernel machine learning for propensity score estimation under complex confounding structures.
Pharmaceutical statistics. [DOI] 10.1002/pst.2105. [PMID] 33619894.
2021
Predicting long-term postsurgical pain by examining the evolution of acute pain.
European journal of pain (London, England). 25(3):624-636 [DOI] 10.1002/ejp.1698. [PMID] 33171546.
2021
Slow Dynamics of Acute Postoperative Pain Intensity Time Series Determined via Wavelet Analysis Are Associated With the Risk of Severe Postoperative Day 30 Pain.
Anesthesia and analgesia. 132(5):1465-1474 [DOI] 10.1213/ANE.0000000000005385. [PMID] 33591118.
2020
AAPM Virtual Issue on Innovation and Technology.
Pain medicine (Malden, Mass.). 21(4) [DOI] 10.1093/pm/pnaa031. [PMID] 32096541.
2020
Artificial Intelligence and Surgical Decision-making.
JAMA surgery. 155(2):148-158 [DOI] 10.1001/jamasurg.2019.4917. [PMID] 31825465.
2020
Bias and ethical considerations in machine learning and the automation of perioperative risk assessment.
British journal of anaesthesia. 125(6):843-846 [DOI] 10.1016/j.bja.2020.07.040. [PMID] 32838979.
2020
Decision analysis and reinforcement learning in surgical decision-making.
Surgery. 168(2):253-266 [DOI] 10.1016/j.surg.2020.04.049. [PMID] 32540036.
2020
Forty-two Million Ways to Describe Pain: Topic Modeling of 200,000 PubMed Pain-Related Abstracts Using Natural Language Processing and Deep Learning-Based Text Generation.
Pain medicine (Malden, Mass.). 21(11):3133-3160 [DOI] 10.1093/pm/pnaa061. [PMID] 32249306.
2020
Intelligent, Autonomous Machines in Surgery.
The Journal of surgical research. 253:92-99 [DOI] 10.1016/j.jss.2020.03.046. [PMID] 32339787.
2020
Joint Distribution and Transitions of Pain and Activity in Critically Ill Patients.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2020:4534-4538 [DOI] 10.1109/EMBC44109.2020.9176453. [PMID] 33019002.
2020
Multiobjective optimization challenges in perioperative anesthesia: A review.
Surgery. [DOI] 10.1016/j.surg.2020.11.005. [PMID] 33334583.
2020
Opportunities for machine learning to improve surgical ward safety.
American journal of surgery. 220(4):905-913 [DOI] 10.1016/j.amjsurg.2020.02.037. [PMID] 32127174.
2020
Pain and Physical Activity Association in Critically Ill Patients
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2020:5696-5699 [DOI] 10.1109/EMBC44109.2020.9176227. [PMID] 33019268.
2020
Phenotyping Cognitive Impairment using Graphomotor and Latency Features in Digital Clock Drawing Test.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2020:5657-5660 [DOI] 10.1109/EMBC44109.2020.9176469. [PMID] 33019260.
2020
Risk of Opioid Overdose Associated With Concomitant Use of Opioids and Skeletal Muscle Relaxants: A Population-Based Cohort Study.
Clinical pharmacology and therapeutics. 108(1):81-89 [DOI] 10.1002/cpt.1807. [PMID] 32022906.
2019
Chronic opioid use in patients undergoing treatment for oropharyngeal cancer.
The Laryngoscope. 129(9):2087-2093 [DOI] 10.1002/lary.27791. [PMID] 30613983.
2019
Clock Drawing Performance Slows for Older Adults After Total Knee Replacement Surgery.
Anesthesia and analgesia. 129(1):212-219 [DOI] 10.1213/ANE.0000000000003735. [PMID] 30273231.
2019
Emergency Department Airway Management Responsibilities in the United States.
Anesthesia and analgesia. 128(2):296-301 [DOI] 10.1213/ANE.0000000000003851. [PMID] 30300176.
2019
Feasibility and Rationale for Incorporating Frailty and Cognitive Screening Protocols in a Preoperative Anesthesia Clinic.
Anesthesia and analgesia. 129(3):830-838 [DOI] 10.1213/ANE.0000000000004190. [PMID] 31425227.
2019
Intelligent ICU for Autonomous Patient Monitoring Using Pervasive Sensing and Deep Learning.
Scientific reports. 9(1) [DOI] 10.1038/s41598-019-44004-w. [PMID] 31142754.
2019
Pilot Study: Neurocognitive Disorders and Colonoscopy in Older Adults.
Anesthesia and analgesia. 129(3):e89-e93 [DOI] 10.1213/ANE.0000000000004212. [PMID] 31425226.
2019
Primer on machine learning: utilization of large data set analyses to individualize pain management.
Current opinion in anaesthesiology. 32(5):653-660 [DOI] 10.1097/ACO.0000000000000779. [PMID] 31408024.
2019
The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Diagnostic Criteria for Acute Pain Conditions: An Introduction.
The journal of pain. 20(7):743-745 [DOI] 10.1016/j.jpain.2018.12.002. [PMID] 30639193.
2019
Trends, Patient and Prescriber Characteristics in Gabapentinoid Use in a Sample of United States Ambulatory Care Visits from 2003 to 2016.
Journal of clinical medicine. 9(1) [DOI] 10.3390/jcm9010083. [PMID] 31905718.
2018
Deep EHR: A Survey of Recent Advances in Deep Learning Techniques for Electronic Health Record (EHR) Analysis.
IEEE journal of biomedical and health informatics. 22(5):1589-1604 [DOI] 10.1109/JBHI.2017.2767063. [PMID] 29989977.
2018
Transition Icons for Time-Series Visualization and Exploratory Analysis.
IEEE journal of biomedical and health informatics. 22(2):623-630 [DOI] 10.1109/JBHI.2017.2704608. [PMID] 28534797.
2017
Age differences in salivary markers of inflammation in response to experimental pain: does venipuncture matter?
Journal of pain research. 10:2365-2372 [DOI] 10.2147/JPR.S138460. [PMID] 29042812.
2017
Age Differences in the Time Course and Magnitude of Changes in Circulating Neuropeptides After Pain Evocation in Humans.
The journal of pain. 18(9):1078-1086 [DOI] 10.1016/j.jpain.2017.04.006. [PMID] 28461253.
2017
Characterizations of Temporal Postoperative Pain Signatures With Symbolic Aggregate Approximations.
The Clinical journal of pain. 33(1):1-11 [PMID] 27153359.
View on: PubMed
2017
DisTeam: A decision support tool for surgical team selection.
Artificial intelligence in medicine. 76:16-26 [DOI] 10.1016/j.artmed.2017.02.002. [PMID] 28363285.
2017
Economic Considerations of Acute Pain Medicine Programs.
Techniques in orthopaedics (Rockville, Md.). 32(4):217-225 [DOI] 10.1097/BTO.0000000000000241. [PMID] 29403150.
2017
Goals and Objectives to Optimize the Value of an Acute Pain Service in Perioperative Pain Management.
Techniques in orthopaedics (Rockville, Md.). 32(4):200-208 [DOI] 10.1097/BTO.0000000000000245. [PMID] 29403149.
2017
The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.
Pain medicine (Malden, Mass.). 18(5):947-958 [DOI] 10.1093/pm/pnx019. [PMID] 28482098.
2017
The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.
The journal of pain. 18(5):479-489 [DOI] 10.1016/j.jpain.2017.02.421. [PMID] 28495013.
2016
Acute and Chronic Kidney Disease and Cardiovascular Mortality After Major Surgery.
Annals of surgery. 264(6):987-996 [PMID] 26756753.
View on: PubMed
2016
Deep neural network architectures for forecasting analgesic response.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2016:2966-2969 [DOI] 10.1109/EMBC.2016.7591352. [PMID] 28268935.
2016
Ising Model of the Chronification of Acute Pain.
Pain medicine (Malden, Mass.). 17(1):3-4 [PMID] 26398867.
View on: PubMed
2016
Locating the optimal internal jugular target site for central venous line placement.
Journal of clinical anesthesia. 33:198-202 [DOI] 10.1016/j.jclinane.2016.03.070. [PMID] 27555164.
2016
Markov chain evaluation of acute postoperative pain transition states.
Pain. 157(3):717-728 [DOI] 10.1097/j.pain.0000000000000429. [PMID] 26588689.
2016
On variance estimate for covariate adjustment by propensity score analysis.
Statistics in medicine. 35(20):3537-48 [DOI] 10.1002/sim.6943. [PMID] 26999553.
2016
The time course of acute pain in hospitalized patients: exciting progress in data and methods.
Pain. 157(12):2623-2624 [DOI] 10.1097/j.pain.0000000000000714. [PMID] 27682211.
2016
Time to Onset of Sustained Postoperative Pain Relief (SuPPR): Evaluation of a New Systems-level Metric for Acute Pain Management.
The Clinical journal of pain. 32(5):371-9 [DOI] 10.1097/AJP.0000000000000285. [PMID] 26247416.
2015
Acute Pain Medicine in the United States: A Status Report.
Pain medicine (Malden, Mass.). 16(9):1806-26 [DOI] 10.1111/pme.12760. [PMID] 26535424.
2015
Clinically derived early postoperative pain trajectories differ by age, sex, and type of surgery.
Pain. 156(4):609-617 [DOI] 10.1097/01.j.pain.0000460352.07836.0d. [PMID] 25790453.
2015
Incidence and mortality trends of aspiration pneumonia in Parkinson’s disease in the United States, 1979-2010.
Parkinsonism & related disorders. 21(9):1082-6 [DOI] 10.1016/j.parkreldis.2015.06.020. [PMID] 26154915.
2015
Teaching a Machine to Feel Postoperative Pain: Combining High-Dimensional Clinical Data with Machine Learning Algorithms to Forecast Acute Postoperative Pain.
Pain medicine (Malden, Mass.). 16(7):1386-401 [DOI] 10.1111/pme.12713. [PMID] 26031220.
2015
The painful tweet: text, sentiment, and community structure analyses of tweets pertaining to pain.
Journal of medical Internet research. 17(4) [DOI] 10.2196/jmir.3769. [PMID] 25843553.
2014
Are anesthesia start and end times randomly distributed? The influence of electronic records.
Journal of clinical anesthesia. 26(4):264-70 [DOI] 10.1016/j.jclinane.2013.10.016. [PMID] 24856798.
2014
Geospatial analysis of hospital consumer assessment of healthcare providers and systems pain management experience scores in U.S. hospitals.
Pain. 155(5):1016-1026 [DOI] 10.1016/j.pain.2014.02.003. [PMID] 24525273.
2014
Of rough starts and smooth finishes: correlations between post-anesthesia care unit and postoperative days 1-5 pain scores.
Pain medicine (Malden, Mass.). 15(2):306-15 [DOI] 10.1111/pme.12287. [PMID] 24308744.
2014
Retrospective computed tomography mapping of intrapleural air may demonstrate optimal window for ultrasound diagnosis of pneumothorax.
Journal of intensive care medicine. 29(6):342-7 [DOI] 10.1177/0885066613488735. [PMID] 23753251.
2014
Sex differences in the incidence of severe pain events following surgery: a review of 333,000 pain scores.
Pain medicine (Malden, Mass.). 15(8):1390-404 [DOI] 10.1111/pme.12498. [PMID] 25039440.
2013
A comparison of 4 airway devices on cervical spine alignment in cadaver models of global ligamentous instability at c1-2.
Anesthesia and analgesia. 117(1):126-32 [DOI] 10.1213/ANE.0b013e318279b37a. [PMID] 23354337.
2013
Acute pain medicine in anesthesiology.
F1000prime reports. 5 [DOI] 10.12703/P5-54. [PMID] 24381730.
2013
The evolution and practice of acute pain medicine.
Pain medicine (Malden, Mass.). 14(1):124-44 [DOI] 10.1111/pme.12015. [PMID] 23241132.
2012
Primary payer status is associated with the use of nerve block placement for ambulatory orthopedic surgery.
Regional anesthesia and pain medicine. 37(3):254-61 [DOI] 10.1097/AAP.0b013e31824889b6. [PMID] 22430024.
2012
Social network analysis and quantification of a prototypical acute pain medicine and regional anesthesia service.
Pain medicine (Malden, Mass.). 13(6):808-19 [DOI] 10.1111/j.1526-4637.2012.01379.x. [PMID] 22568636.
2012
Use of machine-learning classifiers to predict requests for preoperative acute pain service consultation.
Pain medicine (Malden, Mass.). 13(10):1347-57 [DOI] 10.1111/j.1526-4637.2012.01477.x. [PMID] 22958457.
2011
Artifactual increase in journal self-citation.
Anesthesia and analgesia. 113(2):378-82 [DOI] 10.1213/ANE.0b013e31821d72e5. [PMID] 21596873.
2011
Noninvasive tissue oxygen saturation determined by near-infrared spectroscopy following peripheral nerve block.
Acta anaesthesiologica Scandinavica. 55(10):1239-46 [DOI] 10.1111/j.1399-6576.2011.02533.x. [PMID] 22092129.
2011
The progression of regional anesthesia into acute and perioperative pain medicine.
International anesthesiology clinics. 49(3):104-9 [DOI] 10.1097/AIA.0b013e31821a0272. [PMID] 21697674.
2011
Use of machine learning theory to predict the need for femoral nerve block following ACL repair.
Pain medicine (Malden, Mass.). 12(10):1566-75 [DOI] 10.1111/j.1526-4637.2011.01228.x. [PMID] 21899717.
2011
Virtual humans versus standardized patients: which lead residents to more correct diagnoses?
Academic medicine : journal of the Association of American Medical Colleges. 86(3):384-8 [DOI] 10.1097/ACM.0b013e318208803f. [PMID] 21248598.
2010
New trends in regional anesthesia for shoulder surgery: Avoiding devastating complications.
International journal of shoulder surgery. 4(1):1-7 [DOI] 10.4103/0973-6042.68410. [PMID] 20922086.
2010
Robot-assisted airway support: a simulated case.
Anesthesia and analgesia. 111(4):929-31 [DOI] 10.1213/ANE.0b013e3181ef73ec. [PMID] 20870983.
2010
Technical communication: robot-assisted regional anesthesia: a simulated demonstration.
Anesthesia and analgesia. 111(3):813-6 [DOI] 10.1213/ANE.0b013e3181e66386. [PMID] 20581161.
2005
Severe thrombocytopenia in a neonate with congenital HIV infection.
The Journal of pediatrics. 146(3):408-13 [PMID] 15756230.
View on: PubMed

Grants

Apr 2021 ACTIVE
Intelligent Intensive Care Unit (I2CU): Pervasive Sensing and Artificial Intelligence for Augmented Clinical Decision-making
Role: Co-Investigator
Funding: NATL INST OF HLTH NIBIB
Jul 2020 ACTIVE
Together Transforming and Translating Discovery to Improve Health
Role: Project Manager
Funding: NATL INST OF HLTH NCATS
Sep 2019 ACTIVE
University of Florida Early Phase Pain Investigation Clinical Center
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
May 2019 ACTIVE
Impact of total knee replacement surgery on trajectory of cognitive decline in individuals with mild cognitive impairment (MCI)
Role: Co-Investigator
Funding: FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER
Feb 2019 ACTIVE
Autonomous Pain Recognition in Non-Verbal and Critically Ill Patients
Role: Co-Investigator
Funding: NATL INST OF HLTH NIBIB
Sep 2018 – Dec 2020
Using intuitive eLearning to Provide Personalized Training to Informal Caregivers of Patients with Dementia During the Discharge Process
Role: Co-Investigator
Funding: CENTRE FOR AGING AND BRAIN HEALTH INNOVA
Aug 2017 ACTIVE
PRECEDE: PREsurgical Cognitive Evaluation via Digital clockfacEdrawing
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Jul 2015 ACTIVE
Finding Good TEMporal PostOperative pain Signatures (TEMPOS)
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Jul 2012 – Jun 2016
Use of Machine Learning Classifiers to Forecast Severe Acute Postoperative Pain Following Cancer Surgery.
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS

Patents

Issued November 2016
Apparatuses and Methods for Supporting an Umbilicus
#9,492,175

Education

MS, Clinical and Translational Research
2012 · University of Florida
Fellowship, Regional Anesthesia and Acute Pain Medicine
2010 · University of Florida
Residency, Anesthesiology
2009 · University of Florida
MD
2005 · University of Florida

Teaching Profile

Courses Taught
2020
PHC7918 Independent Study
2018
CIS7979 Advanced Research

Contact Details

Phones:
Business:
(352) 273-7844
Emails:
Business:
ptighe@ufl.edu