Sylvain Doré, PhD, FAHA

UF Department of Anethesiology Celebration of Research at the Founder's GalleryProfessor of Anesthesiology, Neurology, Psychiatry, Psychology, Pharmaceutics and Neuroscience
Director of Research Programs, Department of Anesthesiology;
Investigator, McKnight Brain Institute and CTRND

Contact Information

Department of Anesthesiology
College of Medicine, University of Florida
PO Box 100254
1600 SW Archer Road
Gainesville, FL 32610

Office Phone


Lab Phone



Administrative Assistant 

Antoinette Noel
Phone: (352) 273-8952

Sylvain Doré, PhD is a Professor and Program Director of Research Operations in the Department of Anesthesiology, as well as Professor of Neurology, Psychiatry, Pharmaceutics, and Neuroscience, at the University of Florida, College of Medicine.

Dr. Doré attained his PhD, in biomedical science, from the University of Montreal and an MS degree in pharmacology at the University of Quebec. He received post-PhD training in psychiatry at McGill University, as well as post-PhD training in neuroscience at Johns Hopkins University.

Dr. Doré’s research pertains to studying new effective mechanisms that limit neuronal dysfunction associated with ischemic and hemorrhagic stroke, Alzheimer disease (AD), aging, and various other neurological disorders. His objective is focused on understanding the protective role of heme metabolites in the brain using cellular/molecular techniques and various models of stroke, Alzheimer disease, and aging. New knowledge is gained specifically, by investigating the action and the role of activity of the heme oxygenase enzyme and its unique bioactive metabolites, namely, carbon monoxide, iron, biliverdin, and bilirubin. His overall goal is to slow down the progression of the disease, and ultimately stop it.

Winning the Chairman Award for Outstanding Service and Dedication at the Department of Anesthesiology, University of Florida, is amongst his many accomplishments. He is involved in many ad hoc journal peer review activities and sits on the editorial board of multiple journals, including Frontiers in Neuroscience, Neurotoxicity Research, Faculty of 1000, World Journal of Cardiology, International Journal of Clinical and Experimental Medicine, Translational Neuroscience, and International Journal of Clinical Anesthesiology.

Dr. Doré is a well-published author with over 126 scholarly publications mapping across 13 different disciplines. He has received many grant awards funding his research, and has filed patents for five intellectual properties.


1999 Post-Doc – Neuroscience (Sol Snyder) John Hopkins University Baltimore, MD
1996 Post-Doc – Psychiatry (Rémi Quirion) McGill University Montreal, Canada
1994 PhD – Biomedical Sciences University of Montreal Montreal, Canada
1990 MS – Pharmacology University of Quebec Montreal, Canada
1988 BS – Biochemistry University of Montreal Montreal, Canada

Research Interest

Neurodigenerative disorders, ischemic stroke, Alzheimer’s disease, aging, heme oxygenase, prostaglandins

Special Accomplishments

2014 University of Florida College of Medicine Exemplary Teachers Award
2014 FAHA Recognition for the American Heart and Stroke Association
2011 Chairman Award for Outstanding Service and Dedication to the Department of Anesthesiology

Selected Publications

PubMed hyperlink


Join the team!
Volunteers (Undergrads or MD trained) are now being accepted for conducting research in Dr. Sylvain Doré’s lab. The team focuses on investigating novel treatments of neurological disorders. Specifically, current projects involve the utilization of various preclinical mouse models to uncover the neurobiological processes of ischemic and hemorrhagic strokes, and those associated with Aging, Alzheimer disease and other related neurovascular cognitive impairments. The lab is especially interested in inflammation, antioxidants and natural products. Volunteers will have the opportunity to learn about the rigorous process of scientific inquiry and gain hands-on experience conducting experiments (for example, PCR-genotyping, perfusion, brain harvesting, slicing, staining, and quantification/analysis, etc). Those interested will be asked to commit an average of 4 X 4h-block/week; additionally, summer “internship” is encouraged. Please email us if you are interested in volunteering or would like more information about this exciting opportunity