Marc O Maybauer

Marc O Maybauer, M.D., Ph.D.

Professor of Anesthesiology; Chief, Critical Care Medicine Division

Department: MD-ANEST CRITICAL CARE MED
Business Phone: (352) 273-6575
Business Email: mmaybauer@ufl.edu

About Marc O Maybauer

My name is Marc Maybauer, M.D., Ph.D., and I joined the department of anesthesiology as a professor and chief of the critical care medicine division in 2023. My specialties include critical care medicine, emergency medicine, cardiothoracic anesthesia, transesophageal echocardiography and mechanical circulatory support. I completed medical school at Justus Liebig University in Germany and residencies at the university hospitals in Mainz and Ulm. I then went on to a critical care medicine fellowship at the University of Texas Medical Branch in Galveston and a cardiac anesthesia fellowship at the Oxford Heart Centre with Oxford University Hospitals in the UK.

I am the editor of the textbook Extracorporeal Membrane Oxygenation – A Problem Based Learning Approach and have an interest in teaching on the subject. My scientific work initially began with airway management and the pathophysiology of septic and circulatory shock before developing into ARDS and ECMO. I have also been involved in work on the development of the EasyTube and vasopressin V1a receptor agonists. Most recently, I have taken an interest in anticoagulation for patients with ECMO support and further development of the ProtekDuo RVAD/ECMO cannula.

After more than 20 years in anesthesia and critical care medicine, I am fortunate to have gained significant experience in all fields of my specialty while learning from various mentors and I am excited to share my knowledge and contribute to the education of the next generation of students and trainees.

Publications

2022
Argatroban Anticoagulation for Adult Extracorporeal Membrane Oxygenation: A Systematic Review.
Journal of intensive care medicine. 37(4):459-471 [DOI] 10.1177/0885066621993739. [PMID] 33653194.
2022
Direct Thrombin Inhibition in Extracorporeal Membrane Oxygenation.
The International journal of artificial organs. 45(7):652-655 [DOI] 10.1177/03913988221091292. [PMID] 35411823.
2022
Incidence and outcome of anaphylaxis in cardiac surgical patients.
Annals of cardiac anaesthesia. 25(3):323-329 [DOI] 10.4103/aca.aca_170_21. [PMID] 35799561.
2022
The novel ProtekDuo ventricular assist device: Configurations, technical aspects, and present evidence.
Perfusion. [DOI] 10.1177/02676591221090607. [PMID] 35619541.
2022
The ProtekDuo as double lumen return cannula in V-VP ECMO configuration: A first-in-man method description.
Annals of cardiac anaesthesia. 25(2):217-219 [DOI] 10.4103/aca.aca_49_21. [PMID] 35417975.
2021
Veno-arteriovenous extracorporeal membrane oxygenation-A single center experience.
Artificial organs. 45(12):1554-1561 [DOI] 10.1111/aor.14070. [PMID] 34519067.
2020
Anaesthetic management of myasthenia gravis in coronary artery bypass grafting.
Annals of cardiac anaesthesia. 23(2):209-211 [DOI] 10.4103/aca.ACA_176_18. [PMID] 32275037.
2020
Mechanical cardiopulmonary resuscitation for venoarterial ECMO implantation in pulmonary embolism complicated by type B aortic dissection and retroperitoneal hemorrhage.
Journal of cardiac surgery. 35(10):2821-2824 [DOI] 10.1111/jocs.14782. [PMID] 33043655.
2019
Extra-corporeal membrane oxygenation in aortic surgery and dissection: A systematic review.
World journal of critical care medicine. 8(8):135-147 [DOI] 10.5492/wjccm.v8.i8.135. [PMID] 31942440.
2019
Meta-Analysis of Electroacupuncture in Cardiac Anesthesia and Intensive Care.
Journal of intensive care medicine. 34(8):652-661 [DOI] 10.1177/0885066617708558. [PMID] 28569130.
2019
Percutaneous venoarterial extracorporeal membrane oxygenation as a bridge to double valve implantation in acute biventricular heart failure with profound cardiogenic shock.
Journal of cardiac surgery. 34(12):1664-1666 [DOI] 10.1111/jocs.14255. [PMID] 31508845.
2019
Perspectives on adjunctive use of ketamine for analgosedation during extracorporeal membrane oxygenation.
Expert opinion on drug metabolism & toxicology. 15(5):349-351 [DOI] 10.1080/17425255.2019.1593963. [PMID] 30913933.
2018
Extracorporeal membrane oxygenation in severe respiratory failure resulting from burns and smoke inhalation injury.
Burns : journal of the International Society for Burn Injuries. 44(5):1091-1099 [DOI] 10.1016/j.burns.2018.01.022. [PMID] 29500117.
2018
Perioperative management of critical right ventricular inflow obstruction from right atrial rhabdomyoma.
Annals of cardiac anaesthesia. 21(4):430-432 [DOI] 10.4103/aca.ACA_233_17. [PMID] 30333341.
2017
Bivalirudin for Alternative Anticoagulation in Extracorporeal Membrane Oxygenation: A Systematic Review.
Journal of intensive care medicine. 32(5):312-319 [DOI] 10.1177/0885066616656333. [PMID] 27356945.
2017
Effects of Acupuncture in Anesthesia for Craniotomy: A Meta-Analysis.
Journal of neurosurgical anesthesiology. 29(3):219-227 [DOI] 10.1097/ANA.0000000000000290. [PMID] 26967459.
2017
Extracorporeal membrane oxygenation in adult congenital heart disease: a case series and literature review.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine. 19(Suppl 1):15-20 [PMID] 29084497.
2017
Incidence and Factors Associated with Burnout in Anesthesiology: A Systematic Review.
BioMed research international. 2017 [DOI] 10.1155/2017/8648925. [PMID] 29318155.
2017
The role of vasopressin and the vasopressin type V1a receptor agonist selepressin in septic shock.
Journal of critical care. 40:41-45 [DOI] 10.1016/j.jcrc.2017.03.008. [PMID] 28319910.
2016
Extracorporeal Membrane Oxygenation in Pregnant and Postpartum Women With H1N1-Related Acute Respiratory Distress Syndrome: A Systematic Review and Meta-analysis.
Obstetrics and gynecology. 127(2):241-7 [DOI] 10.1097/AOG.0000000000001236. [PMID] 26942349.
2016
Oxygenation via a Biventricular Assist Device for Emergency Airway Management.
A & A case reports. 6(9):288-90 [DOI] 10.1213/XAA.0000000000000310. [PMID] 27136082.
2016
The Easytube for airway management: a systematic review of clinical and simulation studies.
Journal of clinical anesthesia. 31:215-22 [DOI] 10.1016/j.jclinane.2016.01.039. [PMID] 27185715.
2015
A new frontier for an old drug? A word of caution for beta-blockers in sepsis!
Current medical research and opinion. 31(10):1829-30 [DOI] 10.1185/03007995.2015.1085371. [PMID] 26296157.
2015
Cerebral oximetry and return of spontaneous circulation after cardiac arrest: A systematic review and meta-analysis.
Resuscitation. 94:67-72 [DOI] 10.1016/j.resuscitation.2015.06.023. [PMID] 26159613.
2015
Do initial tidal volumes impact acute respiratory distress syndrome development in patients intubated in the emergency department?
Journal of critical care. 30(2):421-2 [DOI] 10.1016/j.jcrc.2014.12.016. [PMID] 25700967.
2015
Limited echocardiography in the management of critically ill patients in shock.
Journal of critical care. 30(2) [DOI] 10.1016/j.jcrc.2014.11.010. [PMID] 25573282.
2015
The role of neuromuscular blockade in patients with traumatic brain injury: a systematic review.
Neurocritical care. 22(2):325-34 [DOI] 10.1007/s12028-014-0061-1. [PMID] 25182388.
2014
Effects and timing of tranexamic acid on transfusion requirements in patients undergoing cardiac surgery with cardiopulmonary bypass.
Anesthesiology. 121(4) [DOI] 10.1097/ALN.0000000000000378. [PMID] 25247858.
2014
Optimal management of the critically ill: anaesthesia, monitoring, data capture, and point-of-care technological practices in ovine models of critical care.
BioMed research international. 2014 [DOI] 10.1155/2014/468309. [PMID] 24783206.
2014
Short-acting β-blocker administration in patients with septic shock.
JAMA. 311(7) [DOI] 10.1001/jama.2014.315. [PMID] 24549557.
2014
The selective vasopressin type 1a receptor agonist selepressin (FE 202158) blocks vascular leak in ovine severe sepsis*.
Critical care medicine. 42(7):e525-e533 [DOI] 10.1097/CCM.0000000000000300. [PMID] 24674922.
2014
Transesophageal echocardiography in the management of burn patients.
Burns : journal of the International Society for Burn Injuries. 40(4):630-5 [DOI] 10.1016/j.burns.2013.08.032. [PMID] 24035579.
2013
A meta-analysis of analgesic and sedative effects of dexmedetomidine in burn patients.
Burns : journal of the International Society for Burn Injuries. 39(4):625-31 [DOI] 10.1016/j.burns.2013.01.008. [PMID] 23465796.
2013
Extracorporeal membrane oxygenation in burn and smoke inhalation injury.
Burns : journal of the International Society for Burn Injuries. 39(3):429-35 [DOI] 10.1016/j.burns.2012.08.006. [PMID] 23062623.
2013
Intracardiac echocardiography guided transeptal catheter injection of microspheres for assessment of cerebral microcirculation in experimental models.
Cardiology research and practice. 2013 [DOI] 10.1155/2013/595838. [PMID] 24102032.
2013
Off-pump or on-pump coronary-artery bypass grafting.
The New England journal of medicine. 369(2) [DOI] 10.1056/NEJMc1306329. [PMID] 23841739.
2013
Routine screening and anticipation of difficult airways in the critical care setting.
Minerva anestesiologica. 79(8):965-6 [PMID] 23449244.
2012
Combined recombinant human activated protein C and ceftazidime prevent the onset of acute respiratory distress syndrome in severe sepsis.
Shock (Augusta, Ga.). 37(2):170-6 [DOI] 10.1097/SHK.0b013e31823ca8ee. [PMID] 22089200.
2012
Incidence and outcome of tube thoracostomy positioning in trauma patients.
Prehospital emergency care. 16(2):237-41 [DOI] 10.3109/10903127.2011.615975. [PMID] 21967410.
2012
Intramuscular versus intravenous benzodiazepines for status epilepticus.
The New England journal of medicine. 366(20):1943-4; author reply 1944 [DOI] 10.1056/NEJMc1203428. [PMID] 22591304.
2012
Role of the PPAR-α agonist fenofibrate in severe pediatric burn.
Burns : journal of the International Society for Burn Injuries. 38(4):481-6 [DOI] 10.1016/j.burns.2011.12.004. [PMID] 22226866.
2011
Cardiopulmonary effects of low-dose arginine vasopressin in ovine acute lung injury.
Critical care medicine. 39(2):357-63 [DOI] 10.1097/CCM.0b013e3181feb802. [PMID] 21057315.
2011
Children with burn injuries–assessment of trauma, neglect, violence and abuse.
Journal of injury & violence research. 3(2):98-110 [DOI] 10.5249/jivr.v3i2.91. [PMID] 21498973.
2011
Impact of bronchial circulation on bronchial exudates following combined burn and smoke inhalation injury in sheep.
Burns : journal of the International Society for Burn Injuries. 37(3):465-73 [DOI] 10.1016/j.burns.2010.11.005. [PMID] 21195551.
2011
The peroxynitrite catalyst WW-85 improves microcirculation in ovine smoke inhalation injury and septic shock.
Burns : journal of the International Society for Burn Injuries. 37(5):842-50 [DOI] 10.1016/j.burns.2010.12.020. [PMID] 21345593.
2011
The peroxynitrite catalyst WW-85 improves pulmonary function in ovine septic shock.
Shock (Augusta, Ga.). 35(2):148-55 [DOI] 10.1097/SHK.0b013e3181eb4556. [PMID] 20577150.
2011
Vasopressin analogues and V1a receptor agonists in septic shock.
Inflammation research : official journal of the European Histamine Research Society … [et al.]. 60(5):425-7 [DOI] 10.1007/s00011-011-0314-9. [PMID] 21312051.
2010
A novel antibiotic based long-term model of ovine smoke inhalation injury and septic shock.
Burns : journal of the International Society for Burn Injuries. 36(7):1050-8 [DOI] 10.1016/j.burns.2010.01.009. [PMID] 20395054.
2010
Best vasopressor for advanced vasodilatory shock: should vasopressin be part of the mix?
Intensive care medicine. 36(9):1484-7 [DOI] 10.1007/s00134-010-1942-1. [PMID] 20593277.
2010
Management of acute smoke inhalation injury.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine. 12(1):53-61 [PMID] 20196715.
2010
Recombinant human activated protein C attenuates cardiovascular and microcirculatory dysfunction in acute lung injury and septic shock.
Critical care (London, England). 14(6) [DOI] 10.1186/cc9342. [PMID] 21110850.
2010
Role of chelatable iron versus myoglobin in oxidative stress after crush trauma.
Shock (Augusta, Ga.). 33(5):552-3 [DOI] 10.1097/SHK.0b013e3181c24fa7. [PMID] 19789458.
2010
The role of nitric oxide and reactive nitrogen species in experimental ARDS.
Frontiers in bioscience (Scholar edition). 2(1):18-29 [PMID] 20036926.
2009
[Hurricane Ike and the University of Texas Medical Branch Hospital’s evacuation].
Der Anaesthesist. 58(12):1244-51 [DOI] 10.1007/s00101-009-1643-8. [PMID] 19949762.
2009
[Pathophysiology of acute lung injury in severe burn and smoke inhalation injury].
Der Anaesthesist. 58(8):805-12 [DOI] 10.1007/s00101-009-1560-x. [PMID] 19517070.
2009
Cardiovascular collapse and vascular permeability changes in an ovine model of methicillin-resistant Staphylococcus aureus sepsis.
Shock (Augusta, Ga.). 32(6):621-5 [DOI] 10.1097/SHK.0b013e3181a4fd01. [PMID] 19295474.
2009
Catecholamines, vasopressin and markers of acute liver injury in septic shock.
Shock (Augusta, Ga.). 31(2):222-3 [DOI] 10.1097/SHK.0b013e3181890847. [PMID] 19145198.
2009
Comparison of two different techniques of fibreoptic intubation.
European journal of anaesthesiology. 26(4):328-32 [DOI] 10.1097/EJA.0b013e32831ac4ce. [PMID] 19401663.
2009
Pathophysiology, management and treatment of smoke inhalation injury.
Expert review of respiratory medicine. 3(3):283-297 [PMID] 20161170.
2009
Pulmonary vascular permeability changes in an ovine model of methicillin-resistant Staphylococcus aureus sepsis.
Critical care (London, England). 13(1) [DOI] 10.1186/cc7720. [PMID] 19222851.
2009
Radiological validation of tracheal tube insertion depth in out-of-hospital and in-hospital emergency patients.
Anaesthesia. 64(9):973-7 [DOI] 10.1111/j.1365-2044.2009.06007.x. [PMID] 19686482.
2009
Recombinant human activated protein C in acute lung injury: what is the role of bronchial circulation?
Critical care (London, England). 13(1) [DOI] 10.1186/cc7155. [PMID] 19226431.
2009
Who is the bad guy in acute respiratory distress syndrome? Neuronal nitric oxide synthase, inducible nitric oxide synthase, or both?
Critical care medicine. 37(1):363-4 [DOI] 10.1097/CCM.0b013e318192fec3. [PMID] 19112308.
2008
Lung-protective effects of the metalloporphyrinic peroxynitrite decomposition catalyst WW-85 in interleukin-2 induced toxicity.
Biochemical and biophysical research communications. 377(3):786-91 [DOI] 10.1016/j.bbrc.2008.10.066. [PMID] 18951875.
2008
Neuronal nitric oxide synthase inhibition attenuates cardiopulmonary dysfunctions after combined burn and smoke inhalation injury in sheep.
Critical care medicine. 36(4):1196-204 [DOI] 10.1097/CCM.0b013e31816a1a0c. [PMID] 18379246.
2008
Physiology of the vasopressin receptors.
Best practice & research. Clinical anaesthesiology. 22(2):253-63 [PMID] 18683472.
2007
Ceftazidime improves hemodynamics and oxygenation in ovine smoke inhalation injury and septic shock.
Intensive care medicine. 33(7):1219-1227 [DOI] 10.1007/s00134-007-0658-3. [PMID] 17503018.
2007
Recombinant human activated protein C in experimental models of acute lung injury: the timing is critical!
Intensive care medicine. 33(12):2048-50 [PMID] 17671778.
2007
Ventilation strategy, recruitment, and pulmonary bacterial translocation: scientific clearance is open!
Intensive care medicine. 33(10):1687-9 [PMID] 17576530.
2006
[Comparison between the laryngeal tubus S and endotracheal intubation. Simulation of securing the airway in an emergency situation].
Der Anaesthesist. 55(2):154-9 [PMID] 16235073.
2006
[Treatment strategies for acute smoke inhalation injury].
Der Anaesthesist. 55(9):980-2, 984 [PMID] 16826418.
2006
Combined burn and smoke inhalation injury impairs ovine hypoxic pulmonary vasoconstriction.
Critical care medicine. 34(5):1428-36 [PMID] 16540966.
2006
Effects of severe smoke inhalation injury and septic shock on global hemodynamics and microvascular blood flow in sheep.
Shock (Augusta, Ga.). 26(5):489-95 [PMID] 17047520.
2006
Experimental therapies for hypoxic pulmonary vasoconstriction.
Shock (Augusta, Ga.). 25(3) [PMID] 16552366.
2006
Incidence and outcomes of acute lung injury.
The New England journal of medicine. 354(4):416-7; author reply 416 [PMID] 16444810.
2006
Positive end-expiratory pressure ventilation increases extravascular lung water due to a decrease in lung lymph flow.
Anaesthesia and intensive care. 34(3):329-33 [PMID] 16802485.
2006
Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis.
Critical care medicine. 34(9):2432-8 [PMID] 16810106.
2006
Resuscitation with hypertonic saline in burn shock and sepsis.
Critical care medicine. 34(6):1849-50 [PMID] 16715001.
2006
The inhibition of inducible nitric oxide synthase in ovine sepsis model.
Shock (Augusta, Ga.). 25(5):522-7 [PMID] 16680018.
2006
The role of superoxide dismutase in systemic inflammation.
Shock (Augusta, Ga.). 25(2):206-7 [PMID] 16525361.
2005
[An unexpected difficult intubation. Bonfils rigid fiberscope].
Der Anaesthesist. 54(1):35-40 [PMID] 15517112.
2005
Effect of inhaled nitric oxide on pulmonary vascular hyperpermeability in sheep following smoke inhalation.
Burns : journal of the International Society for Burn Injuries. 31(8):1013-9 [PMID] 16288960.
2005
Effects of manganese superoxide dismutase nebulization on pulmonary function in an ovine model of acute lung injury.
Shock (Augusta, Ga.). 23(2):138-43 [PMID] 15665728.
2005
Gentamicin improves hemodynamics in ovine septic shock after smoke inhalation injury.
Shock (Augusta, Ga.). 24(3):226-31 [PMID] 16135961.
2005
Inhalational and acute lung injury.
Shock (Augusta, Ga.). 24 Suppl 1:82-7 [PMID] 16374378.
2005
Selective thromboxane A2 synthase inhibition by OKY-046 prevents cardiopulmonary dysfunction after ovine smoke inhalation injury.
Anesthesiology. 102(5):954-61 [PMID] 15851882.
2005
The EasyTube for airway management in emergencies.
Prehospital emergency care. 9(4):445-8 [PMID] 16263680.
2004
A new device for emergency airway management: the EasyTube.
Resuscitation. 60(3) [PMID] 15050769.
2004
The ATP-sensitive potassium-channel inhibitor glibenclamide improves outcome in an ovine model of hemorrhagic shock.
Shock (Augusta, Ga.). 22(4):387-91 [PMID] 15377897.
2003
Medical support for children’s mass gatherings.
Prehospital and disaster medicine. 18(1):14-9 [PMID] 14694895.

Education

Critical Care Medicine Fellowship
2006 · University of Texas Medical Branch, Galveston
Anesthesiology Residency
2004 · Johannes Gutenberg University of Mainz
Medical Degree
2002 · Justus Liebig University

Contact Details

Phones:
Business:
(352) 273-6575
Emails:
Business:
mmaybauer@ufl.edu
Addresses:
Business Street:
PO Box 100254
1345 CENTER DR
GAINESVILLE FL 32611