Cole Dooley

Cole Dooley, MD

Assistant Professor Of Anesthesiology

Department: MD-ANESTHESIOLOGY-GENERAL
Business Phone: (352) 273-7094
Business Email: fdooley@anest.ufl.edu

About Cole Dooley

My name is Cole Dooley, MD, and I joined the Department of Anesthesiology as an assistant professor in the Divisions of Pediatric Anesthesiology and Perioperative Medicine in 2015. I earned my medical degree from the University of Illinois College of Medicine in Peoria, IL, and completed a transitional internship at St. Vincent Hospital in Indianapolis, IN, before coming to the University of Florida to complete my residency. Following that, I completed my fellowship in pediatric anesthesiology at Arkansas Children’s Hospital UAMS in Little Rock, AR.

I’m an active member of a number of professional organizations, including the Society for Pediatric Anesthesia, the Florida Society of Anesthesiologists, and the American Society of Anesthesiologists. I’ve completed medical mission trip work in Latin America for cleft lip and palate repair and am an authorized Spanish language interpreter here at UF.

In my free time, I like to cook, travel, and read. I’m also a founder of a local non-profit and dedicate a lot of time to fundraising for pediatric cancer research in memory of my daughter.

Board Certifications

  • Anesthesiology
    American Board of Anesthesiology
  • Pediatric Anesthesiology
    American Board of Anesthesiology

Clinical Profile

Specialties
  • Anesthesiology

Publications

2017
A one-pot multicomponent approach to a new series of morphine derivatives and their biological evaluation.
Organic & biomolecular chemistry. 15(37):7796-7801 [DOI] 10.1039/c7ob01924f. [PMID] 28875208.
2016
Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazines.
ACS combinatorial science. 18(1):51-64 [DOI] 10.1021/acscombsci.5b00126. [PMID] 26651386.
2016
Potent μ-Opioid Receptor Agonists from Cyclic Peptides Tyr-c[D-Lys-Xxx-Tyr-Gly]: Synthesis, Biological, and Structural Evaluation.
Journal of medicinal chemistry. 59(3):1239-45 [DOI] 10.1021/acs.jmedchem.5b01899. [PMID] 26789491.
2015
Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities at μ (MOR), δ (DOR), and κ (KOR) Opioid Receptors.
Journal of medicinal chemistry. 58(12):4905-17 [DOI] 10.1021/jm501637c. [PMID] 25996309.
2015
Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities.
European journal of medicinal chemistry. 92:270-81 [DOI] 10.1016/j.ejmech.2014.12.049. [PMID] 25559207.
2014
Synthesis and analgesic activity of alkylated, reduced and constrained oligoheterocyclic peptidomimetic analogs of Leu-enkephalin.
Bioorganic & medicinal chemistry letters. 24(18):4482-4485 [DOI] 10.1016/j.bmcl.2014.07.090. [PMID] 25168746.
2011
Integrating computational and mixture-based screening of combinatorial libraries.
Journal of molecular modeling. 17(6):1473-82 [DOI] 10.1007/s00894-010-0850-1. [PMID] 20853183.
2010
Identification of two novel, potent, low-liability antinociceptive compounds from the direct in vivo screening of a large mixture-based combinatorial library.
The AAPS journal. 12(3):318-29 [DOI] 10.1208/s12248-010-9191-3. [PMID] 20422341.
2009
Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands.
Bioorganic & medicinal chemistry. 17(15):5583-97 [DOI] 10.1016/j.bmc.2009.06.026. [PMID] 19576786.
2008
Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods.
Journal of combinatorial chemistry. 10(1):3-19 [PMID] 18067268.
2006
Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: an example of lead optimization using mixture-based libraries.
Bioorganic & medicinal chemistry letters. 16(16):4331-8 [PMID] 16750366.
1999
Mixture-based synthetic combinatorial libraries.
Journal of medicinal chemistry. 42(19):3743-78 [PMID] 10508425.
1998
Combinatorial chemistry: from peptides and peptidomimetics to small organic and heterocyclic compounds.
Bioorganic & medicinal chemistry letters. 8(17):2273-8 [PMID] 9873527.
1994
An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library.
Science (New York, N.Y.). 266(5193):2019-22 [PMID] 7801131.

Grants

Apr 2023 ACTIVE
Effectiveness of an escape room in teaching pediatric life support skills to interns and residents in Anesthesiology
Role: Principal Investigator
Funding: HEERMANN ANESTHESIA FOU, I

Education

Fellowship, Pediatric Anesthesiology
2015 · Arkansas Children's Hospital
Residency, Anesthesiology
2015 · University of Florida
Internship, Transitional Medicine
2011 · St. Vincent Hospital
MD
2010 · University of Illinois

Contact Details

Phones:
Business:
(352) 273-7094
Emails:
Addresses:
Business Mailing:
1345 SW Center Drive
GAINESVILLE FL 32610
Business Street:
1345 SW Center Drive, PO Box 100254
Gainesville FL 32610