Common Drugs
Intravenous Agents
* Denotes medication that needs to be diluted when drawn-up
Induction Agents/Adjuncts
| Medication | Syringe | Usual Conc. | Dose | Notes |
|---|---|---|---|---|
| Etomidate | 20 mL | 2 mg/mL | 0.2-0.3 mg/kg | Typical induction 14-20 mg |
| Propofol | 20 mL | 10 mg/mL | 2-3 mg/kg | Typical induction 120-200 mg |
| Fentanyl | 5 mL | 50 μg/mL | 1-1.5 μg/kg | Typical induction 100-150 μg |
| Ketamine | 5 mL | 10 mg/mL | 1-2 mg/kg | Multimodal induction 15-30 mg |
| Lidocaine | 5 mL | 10 mg/mL | 0.5-1 mg/kg | Typical induction 50 mg |
| Midazolam | 3 mL | 1 mg/mL | 1-2 mg | Typical pre-medication 2 mg |
Neuromuscular Blocking Agents/Reversal Agents
| MEDICATION | SYRINGE | USUAL CONC. | DOSE | NOTES |
|---|---|---|---|---|
| Cisatracurium | 10 mL | 2 mg/mL | 0.1 mg/kg | |
| Rocuronium | 5 mL | 10 mg/mL | 0.6-1.2 mg/kg | Typical intubation 30-50 mg |
| Succinylcholine | 10 mL | 20 mg/mL | 1-1.5 mg/mL | RSI: 100-150 mL |
| Vecuronium | 10 mL | 1 mg/mL | 0.1 mg/kg | Typical intubation 5-10 mg |
| Glycopyrrolate | 5 mL | 0.2 mg/mL | 0.2-0.9 mg | Given 1 mL:1 mL with neostigmine |
| Neostigmine | 5 mL | 1 mg/mL | 1-4 mg | Given w/glycopyrrolate |
| Sugamadex | 2 mL-5 mL | 100 mg/mL | 2-4 mg/kg | 2 mg/kg if 2 twitches; 4 mg/kg if 0 twitch |
Antiemetics
| MEDICATION | SYRINGE | USUAL CONC. | DOSE | NOTES |
|---|---|---|---|---|
| Metaclopramide | 3 mL | 10 mg/mL | 10 mg | Slow IV push or in IV bag |
| Ondansetron | 3 mL | 2 mg/mL | 4 mg |
Vasoactive Agents
| MEDICATION | SYRINGE | USUAL CONC. | DOSE | NOTES |
|---|---|---|---|---|
| Ephedrine* | 10 mL | 5 mg/mL | 5-10 mg | Single dilution |
| Phenylephrine* | 10 mL | 67-100 μg/mL | 50-100 μg | Double dilution |
| Vasopressin* | 20 mL | 1 unit/mL | 1 unit | Single dilution |
| Esmolol | 10 mL | 10 mg/mL | 10-30 mg | |
| Labetalol | 10 mL | 5 mg/mL | 5-15 mg | |
| Metoprolol | 5 mL | 1 mg/mL | 1-5 mg | –– |
Other Agents
| MEDICATION | SYRINGE | USUAL CONC. | DOSE | NOTES |
|---|---|---|---|---|
| Dexamethasone | 3 mL | 2 mg/mL | 4-8 mg |
Intravenous Infusions
| MEDICATION | USUAL CONC. | Preparation | Starting Dose |
|---|---|---|---|
| Clevidipine | 500 μg/mL | N/A | 1 mg/kg/hr |
| Dobutamine | 1,000 μg/mL | 250 mg in 250 mL of D5W or NS | 2-20 μg/kg/min |
| Dopamine | 1,600 μg/mL | 400 mg in 250 mL of D5W | 5-20 μg/kg/min |
| Epinephrine | 16 μg/mL | 4 mg in 250 mL of D5W or NS | 0.01-0.2 μg/kg/min |
| Nicardipine | 0.1 mg/mL | 25 mg in 250 mL NS | 5-15 mg/hr |
| Nitroglycerine | 200 μg/mL | 50 mg in 250 mL D5W or NS | 0.1-1 μg/kg/min |
| Norepinephrine | 16 μg/mL | 4 mg in 250 mL of D5W or NS | 0.01-0.2 μg/kg/min |
| Phenylephrine | 100 μg/mL | 10 mg in 100 mL NS | 0.1-1.5 μg/kg/min |
| Vasopressin | 1 unit/mL | 100 units in 100 mL NS | 0.03-0.04 units/min |
| Dexmedetomidine | 5 μg/mL | 200 μg in 40 mL NS | 0.1-0.7 μg/kg/hr |
| Propofol | 10 mg/mL | N/A | 20-300 μg/kg/min |
| Remifentanyl | 50 μg/mL | 1 mg in 20 mL NS | 0.1-1.5 μg/kg/min |
| Sufentanil | 5 μg/mL | 50 μg in 10 mL NS | 0.1-1.5 μg/kg/hr |
Analgesics
Source: https://com-dom-hemonc.sites.medinfo.ufl.edu/files/2013/07/Pain.pdf
Adrenergic Agonists and Vasopressors
Beta Blockers
Prophylactic Antibiotic Administration
General Guidelines
*Dosing will vary depending on the clinical situation/surgery performed – check hospital protocols and antibiotic resource guides prior to administration.
In general:
- For surgeries requiring skin incisions
- Cefazolin is the preferred agent (or vancomycin in cases with MRSA)
- For GI surgeries (distal gut) and GU surgeries
- Cefoxitin is the preferred agent
- Cefazolin + Metronidazole for penicillin allergy
- Clindamycin + Gentamicin or Clindamycin + Ciprofloxacin