Antibiotics

Antibiotic Therapy in the Critically Ill

*Please take the quiz below the video to receive credit.

Objectives

  1. Discuss common pathogenic organisms and the classes of antibiotics used to target them
  2. Describe initial empiric antibiotic choices based on location and infection type.
  3. Discuss common mechanisms of resistance and reasons for antibiotic failure.

Articles

Lecture

Quiz

Name(Required)
1. Which of the following are the three most common causes of community acquired pneumonia?(Required)
2. What is the most appropriate antibiotic choice in a patient with NKDA with late HAP as well as other risk factors for multi drug resistance?(Required)
3. What is the most common cause of urinary catheter associated UTI?(Required)
4. What is the preferred antibiotic regimen used to cover for suspected bacteremia or catheter associated infection?(Required)
5. What is the first line therapy recommended for suspected necrotizing soft tissue infection?(Required)
6. What is the antibiotic of choice for known MSSA infection?(Required)
7. Which of the following patient populations would be most at risk for developing a pseudomonal infection intra-abdominally and will need broad spectrum ABX coverage?(Required)
8. Which of the following antibiotics does NOT provide anti-pseudomonal coverage?(Required)
9. True or false: If a patient is growing out an Enterobacter species in their blood and sensitivities show resistant to cefoxitin, this bug is most likely an ampC producer and should be treated as resistant to all other cephalosporins except cefepime.(Required)
10. Which of the following is NOT a common pathogen associated with ESBL production?(Required)

Antibiotics in the ICU Part II

*Please take the quiz below the video to receive credit.

Objectives

  1. Apply Vancomycin and aminoglycoside dosing nomograms to patient care
  2. Facilitate the development of patient-specific pharmacokinetic monitoring plans

Articles

Lecture

Quiz

Name(Required)
1. When administering Gentamycin or Tobramycin, one should aim to achieve a trough level of:(Required)
2. Aminoglycoside concentrates most highly in the:(Required)
3. When measuring trough or peak levels of aminoglycosides, how soon before or after respectively should these levels be obtained?(Required)
4. To use the Hartfort Nomogram, in what time frame following the initial dose of aminoglycosides is the first monitoring level drawn.(Required)
5. What is the half life of Tobramycin and Gentamycin?(Required)
6. The Vancomycin trough goal when treating pneumonia should be:(Required)
7. In a patient with necrotizing fasciitis being treated with vancomycin, zosyn, and clindamycin, whose vancomycin trough level returns at 9 mcg/mL, how should the next Vancomycin dose be adjusted.(Required)
8. In a patient with stable aminoglycoside or vancomycin levels, how often should maintenance trough levels be checked?(Required)
9. In a patient with CrCl greater than 60mL/min, what initial dose of vancomycin should be written for?(Required)
10. For a patient receiving intermittent hemodialysis, Vancomycin levels should be drawn before dialysis is received, while the next dose of Vancomycin should be given following the completion of hemodialysis.(Required)