Jiepei Zhu, MD, PhD

zhuResearch Assistant Professor

Contact information

Department of Anesthesiology
College of Medicine, University of Florida
PO Box 100254
1600 SW Archer Road
Gainesville, FL 32610

Office Phone:




Dr. Zhu is Research Assistant Professor and comes to us from Virginia Commonwealth University School of Medicine in Richmond, where he worked as an Assistant Professor in the Department of Anesthesiology and as a fellow at the Johnson Center for Critical Care and Pulmonary Research. Dr. Zhu earned his medical degree from Hengyang Medical College in Hunan, China; his Master of Science from Jinan University in Guangzhou, China; and his PhD from Virginia Commonwealth University. Dr. Zhu has managed research laboratories, research projects, and mentored and trained laboratory research technicians, fellows, residents, and medical students.


Research Interests

  • Preclinical application of Perfluorocarbon as an oxygen carrier on traumatic brain injury, hemorrhagic shock, and en route care
  • Small and Large Animal Model of Trauma and hemorrhagic shock and resuscitation and monitoring
  • Neuropathological mechanisms and treatment of decompression sickness (Gas embolism)
  • Microcirculation and blood substitute materials in decompression sickness
  • Neuronal plasticity/functional recovery following CNS injury (e.g. ischemia, trauma)
  • Neurotrophic factors and receptors expression/regulation following CNS insults Neurodegenerative diseases (mechanisms, therapeutic manipulation, functional recovery)


2003 Post Doc Fellow Department of Anesthesiology, Virginia Commonwealth University Richmond, VA
2000 Post Doc Fellow Departments of Anatomy & Neurosurgery, Virginia Commonwealth University Richmond, VA
1998 PhD Virginia Commonwealth University Richmond, VA
1987 Master of Science Medical College, Jinan University Guangzhou, China
1982 MD Hengyang Medical College Hengyang, Hunan, China


Awards and Honors

1996-1997 Osterud Award for the outstanding graduate student in Anatomy, Virginia Commonwealth University
1996 Finalist in the 14th Annual Neurotrauma Symposium, Washington, DC
1995 Virginia Neuroscience Society Travel Award
1990-1993  Natural Science Research Foundation of Guangdong Province
1987-1992  Research Foundation of Jinan University
1984-1987 National Funded postgraduate training Program

Selected Publications

  • Smith CR, Parsons JT, Zhu J, Spiess BD. The effect of intravenous perfluorocarbon emulsions on wholebody oxygenation after severe decompression sickness. Undersea and Hyperbaric Medicine, Diving Hyperb Med., 2012 March; 42(1): 10-7.
  • Kao CC, Forbes JA, Jermakowicz WJ, Sun DA, Davis B, Zhu J, Lagrange AH, Konrad PESuppression of Thalamocortical Oscillations Following Traumatic Brain Injury in Rats J Neurosurg. 2012 March; 108(1): imprint.
  • Parsons, JT, Smith, CR, Zhu, J, Spiess, BD, Retinal Angiography: Non-Invasive, Real Time Bubble Assessment from the Ocular Fundus. Undersea and Hyperbaric Medicine, 2009 May-Jun; 36(3):169-81.
  • Zhou Z, Sun D, Levasseur JE, Merenda A, Hamm RJ, Zhu J, Spiess BD, Bullock MR. Perfluorocarbon emulsions improve cognitive recovery after lateral fluid percussion brain injury in rats. Neurosurgery. 2008 Oct;63(4):799-806; discussion 806-7
  • Spiess BD, Zhu J, Pierce B, Weis R, Berger BE, Reses J, Smith CR, Ewbank B, Ward KR. Effects of perfluorocarbon infusion in an anesthetized swine decompression model. J Surg Res. 2009 May 1;153(1):83- 94. Epub 2008 Mar 26.
  • Zhu J, Hullett JB, Somera L, Barbee RW, Ward KR, Berger BE, Spiess BD. Intravenous perfluorocarbon emulsion increases nitrogen washout after venous gas emboli in rabbits. Undersea and Hyperbaric Medicine, 2007 Jan-Feb;34(1):7-20.
  • Reeves TM, Prins ML, Zhu J, Povlishock JT, Phillips LL. Matrix Metalloproteinase Inhibition Alters Functional and Structural Correlates of Deafferentation-Induced Sprouting in the Dentate Gyrus. J Neurosci. 2003 Nov 12;23(32):10182-9.
  • Richard H. Singleton, Jiepei Zhu, James R. Stone, and John T. Povlishock. Traumatically Induced Axotomy Adjacent to the Soma does not Result in Acute Neuronal Death. J. Neuroscience, 2002, 22(3): 791-802 8 Jiepei Zhu’s curriculum vita 2016
  • Jiepei Zhu, Robert Hamm, Thomas Reeves, John Povlishock and Linda Phillips. Chronic Postinjury Administration of L-Deprenyl Improves Cognitive Function and Enhances Neuroplasticity after Traumatic Brain Injury. Experimental Neurology, 2000, 166:136-152
  • Zheng-Wu Jiang, Qin-Zhi Gong, Xiao Di, Jiepei Zhu, Bruce G. Lyeth. Dicyclomine, an M1 Muscarinic antagonist, reduces infarct volume in a rat subdural hematoma model. Brain Research, 2000, 852:37-44