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Bo Ma, Ph.D.

Bo MaAssistant Scientist

 

Contact Information:

University of Florida
College of Medicine
Department of Anesthesiology
1600 SW Archer Road
PO Box 100254
Gainesville, Florida 32610-0254

Office Phone:

(352) 273-5259

Email:


Dr. Bo Ma is an Assistant Scientist in the Department of Anesthesiology at the University of Florida, College of Medicine. Dr. Ma received his PhD from Peking Union Medical College in Neuropharmacology. During his PhD program, Dr. Ma researched medicine treatment on stroke rodent models including the commercial products Nimodipine, the synthetic novel derivate of natural squamosamide, and the extracts of Chinese traditional herb. He then studied Stroke at Johns Hopkins University and Parkinson’s disease at the National Institutes of Health during his Post-Doctoral training. Dr. Ma is now focusing on microglia, the resident immune cells in brain. In NIH, he found that NFAT, a well-studied transcription factor, undergoes mitochondrial translocation in response to prolonged inflammatory stimulation in microglial cells. The results are published in the Journal of Neuroscience.

Education

2013 Post Doctoral Studies  Neuroscience National Institutes of Health, Bethesda MD
2010 Post Doctoral Studies Stroke Johns Hopkins University, Baltimore, MD
2008 PhD Neuropharmacology Peking Union Medical College, Beijing, China

 

Selected Publications

  • Ma B, Yu J, Xie C, Sun L, Lin S, Ding J, Luo J, Cai H. Toll-Like Receptors Promote Mitochondrial Translocation of Nuclear Transcription Factor Nuclear Factor of Activated T-Cells in Prolonged Microglial Activation. The Journal of neuroscience. 2015; 35(30):10799-814.
  • Ma B, Xu L, Pan X, Sun L, Ding J, Xie C, Koliatsos V, Cai H. LRRK2 Modulates Microglial Activity through Regulation of Chemokine (C–X3–C) Receptor 1-mediated Signaling Pathways. Human molecular genetics. 2016; doi: 10.1093/hmg/ddw194.
  • Ma B, Day JP, Phillips HF, Slootsky B, Tolosano E, Doré S. Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage. Journal of Neuroinflammation. 2016; 13:26.
  • Cho HJ, Yu J, Xie C, Rudrabhatla P, Chen X, Wu J, Parisiadou L, Liu G, Sun L, Ma B, Ding J, Liu Z, Cai H. Leucine‐rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export. The EMBO journal. 2014; 33(20):2314-31.
  • Ma B, Li M, Ma T, Liu GT, Zhang J. Neuroprotective effects of compound FLZ in an ischemic model mediated by improving cerebral blood flow and enhancing Hsp27 expression. Brain Research, 2016; 1644:288-95.
  • Singh N*, Ma B*, Leonardo CC, Ahmad AS, Narumiya S, Doré S. Role of PGE2 EP1 receptor in intracerebral hemorrhage-induced brain injury. Neurotoxicity research. 2013; 24(4):549-59. (* equal contribution, cover page).
  • Cho HJ, Liu G, Jin SM, Parisiadou L, Xie C, Yu J, Sun L, Ma B, Ding J, Vancraenenbroeck R, Lobbestael E, Baekelandt V, Taymans JM, He P, Troncoso JC, Shen Y, Cai H. MicroRNA-205 regulates the expression of Parkinson’s disease-related leucine-rich repeat kinase 2 protein. Human molecular genetics. 2013; 22(3):608-20.
  • Ma B, Zhang J. The progress in study of α-, β- and γ-secretase closely related to Alzheimer disease. Journal of International Pharmaceutical Research. 2005; 32(1):22-26.
  • Ma B, Zhang J. Nimodipine treatment to assess a modified mouse model of intracerebral hemorrhage. Brain research. 2006; 1078(1):182-8.188.
  • Ma B, Zhang J, Liu G. Hsp70 and neuroprotection. Chinese Pharmacological Bulletin. 2008; 24(8):984-987.
  • Ma B, Li M, Nong H, Shi J, Liu G, Zhang J. Protective effects of extract of Coeloglossum viride var. bracteatum on ischemia-induced neuronal death and cognitive impairment in rats. Behavioral pharmacology. 2008; 19(4):325-33.
  • Li M, Wang YF, Ma B, Liu GT, Zhang J. Effect and mechanism of Coeloglossum viride var. bracteatum extract on scopolamine-induced deficits of learning and memory behavior of rodents. Acta pharmaceutica Sinica. 2009; 44(5):468-72.