Anatoly Martynyuk, PhD
Professor of Anesthesiology and Neuroscience
Member of the McKnight Brain Institute
University of Florida
College of Medicine
Department of Anesthesiology
1600 SW Archer Road
PO Box 100254
Gainesville, Florida 32610-0254
Dr. Anatoly Martynyuk is a Professor of Anesthesiology and Neuroscience and has been with the University of Florida since 2007. Dr. Martynyuk earned a Master of Science degree from Kiev State University as well as his PhD and DSc in biophysics from Bogomoletz Institute of Physiology in Kiev, Ukraine.
Dr. Martynyuk is a neuro-biologist investigating mechanisms of developmental neurobehavioral effects of neonatal exposure to general anesthetic agents. His outstanding research is evident from publications in highly respected journals, including Anesthesiology, Brain, Circulation, Molecular Psychiatry, Stroke, and others.
Dr. Martynyuk has been a principal investigator on projects funded by the National Institute of General Medicine and National Institute of Neurological Disorders and Stroke. Dr. Martynyuk has extensive collaborative links within the University of Florida and internationally. He currently serves as a foreign collaborator on two research grants funded by the National Natural Science Foundation of China. Dr. Martynyuk is on editorial boards of several scientific journals and serves as a reviewer of research grants for many foreign agencies.
|1995||Postdoctoral Research Fellowship||University of Glasgow||Glasgow, Scotland|
|1992||DSc – Biological Sciences in Biophysics||Bogomoletz Institute of Physiology||Kiev, Ukraine|
|1982||PhD – Biophysics||Bogomoletz Institute of Physiology||Kiev, Ukraine|
|1979||MSc – Biology and Biophysics||Kiev State University||Kiev, Ukraine|
- Mechanisms of developmental effects of neonatal anesthesia
- Mechanisms of brain dysfunction in phenylketonuria
- Therapeutic applications of antiglutamatergic agents with polyvalent action and moderate potency for treatment of neurological and neurocognitive disorders
|2011||Study awarded “Best of Category” for Pediatric Anesthesia, International Anesthesia Research Society Annual Meeting, Vancouver, Canada|
|2001||Howard Hughes Medical Institute BRSP Start-Up Award|
|1992||European Brain Research Organization Fellowship|
|1992||European Neuroscience Association Fellowship|
|1991||European Neuroscience Association Fellowship|
- Xu C, Tan S, Zhang J, Seubert CN, Gravenstein N, Sumners C, Vasilopoulos T, Martynyuk AE. Anesthesia with sevoflurane in neonatal rats: Developmental neuroendocrine abnormalities and alleviating effects of the corticosteroid and Cl– importer antagonists. Psychoneuroendocrinology. 2015 Jun 25;60:173-181.
- Willis J, Zhu W, Perez-Downes J, Tan S, Xu C, Seubert C, Gravenstein N, Martynyuk A. Propofol-induced electroencephalographic seizures in neonatal rats: the role of corticosteroids and γ-aminobutyric acid type A receptor-mediated excitation. Anesth Analg. 2015 Feb;120(2):433-9.
- Tan S, Xu C, Zhu W, Willis J, Seubert CN, Gravenstein N, Sumners C, Martynyuk AE. Endocrine and neurobehavioral abnormalities induced by propofol administered to neonatal rats.Anesthesiology. 2014 Nov;121(5):1010-7.
- Seubert CN, Zhu W, Pavlinec C, Gravenstein N, Martynyuk AE. Developmental effects of neonatal isoflurane and sevoflurane exposure in rats. Anesthesiology. 2013 Aug;119(2):358-64.
- Cao W, Pavlinec C, Gravenstein N, Seubert CN, Martynyuk AE. Roles of aldosterone and oxytocin in abnormalities caused by sevoflurane anesthesia in neonatal rats. Anesthesiology. 2012 Oct;117(4):791-800.
- Cao W, Glushakov A, Shah HP, Mecca AP, Sumners C, Shi P, Seubert CN, Martynyuk AE. Halogenated aromatic amino acid 3,5-dibromo-D: -tyrosine produces beneficial effects in experimental stroke and seizures. Amino Acids. 2011 Apr;40(4):1151-8.
- Martynyuk AE, van Spronsen FJ, Van der Zee EA. Animal models of brain dysfunction in phenylketonuria. Mol Genet Metab. 2010;99 Suppl 1:S100-5.
- Edwards DA, Shah HP, Cao W, Gravenstein N, Seubert CN, Martynyuk AE. Bumetanide alleviates epileptogenic and neurotoxic effects of sevoflurane in neonatal rat brain. Anesthesiology. 2010 Mar;112(3):567-75.
- Cao W, Shah HP, Glushakov AV, Mecca AP, Shi P, Sumners C, Seubert CN, Martynyuk AE. Efficacy of 3,5-dibromo-L-phenylalanine in rat models of stroke, seizures and sensorimotor gating deficit. Br J Pharmacol. 2009 Dec;158(8):2005-13.
- Martynyuk AE, Seubert CN, Yarotskyy V, Glushakov AV, Gravenstein N, Sumners C, Dennis DM. Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders. Recent Pat CNS Drug Discov. 2006 Nov;1(3):261-70.