NAMHR

North American Malignant Hyperthermia Registry

NAMHR logo

The North American Malignant Hyperthermia Registry (NAMHR) was established in 1987 and merged with the Malignant Hyperthermia Association of the United States (MHAUS) in 1995 so that data on malignant hyperthermia (MH) could be stored in a site that is supported by one organization (MHAUS). This consolidation offers greater support for research initiatives.

For more than 20 years, the registry was under the direction of Dr. Barbara W. Brandom at Children’s Hospital in Pittsburgh, PA. Now the University of Florida Department of Anesthesiology has the honor of hosting the registry under the direction of Dr. Nikolaus Gravenstein.

The following individuals comprise the NAMHR team:

  • Director – Nik Gravenstein, MD
  • Assistant Director – Cameron Smith, MD, PhD
  • Registry Manager – Amy M. Gunnett, RN, CCRC
  • Data Manager – Patrick Tighe, MD, MS
  • Data Consultant – Lei Zhang, MS
  • Registry Consultant – Bruce Spiess, MD, FAHA, Judith Wishin, RN, BSN, CCRC and Joyce Myers, MBA

The existing NAMHR consists of:

anesthesia needle

  • more than 3,000 reports of in vitro testing for MH susceptibility
  • over 700 reports of adverse metabolic reactions in anesthetized patients (AMRAs)
  • reports of the experience of individuals who have not had the caffeine halothane contracture test (CHCT) results but have reported other reasons to think that they may be MH susceptible

These reports were sent to the NAMHR by the directors of the centers that performed the specialized diagnostic test of MH susceptibility (CHCT) or genetic analysis, and/or by anesthesiologists whose patients experienced MH or an MH-like episode. There are many potential research uses for these data.

Report Forms

Mail forms to:

The North American Malignant Hyperthermia Registry of MHAUS
University of Florida
Department of Anesthesiology
1345 SW Center Drive
PO Box 100254
Gainesville, FL 32610-0245
Phone number: 888-274-7899
Fax number: 352-392-7029
Contact/Email: Amy M. Gunnett / agunnett@anest.ufl.edu